naa a22 4500 51073328X CHVBK 20180411083000.0 cr unu---uuuuu 180411e20130101xx s 000 0 eng 10.1007/s12039-012-0347-9 doi (NATIONALLICENCE)springer-10.1007/s12039-012-0347-9 Chemistry and antifungal potential of Alantolides from Inula racemosa H [Elektronische Daten] [DALVIR KATARIA, K CHAHAL] Alantolactone and isoalantolactone were isolated from powdered roots of Inula racemosa H. using Soxhlet extraction followed by the column chromatography. Pyrazolines of alantolactone and isoalantolactone were synthesized using diazomethane, diazoethane and diazopropane. The structure elucidation of the compounds were carried out using IR and 1H NMR spectroscopic techniques. All the compounds were screened in vitro for their antifungal potential at various concentrations against Alternaria brassicae and Penicillium italicum using spore germination inhibition technique and against Rhizoctonia solani by poisoned food technique. All the compounds exhibited fairly good fungitoxicity against the test fungi with ED50 values of less than 500μgmL − 1. Graphical Abstract Alantolactone (1) and isoalantolactone were treated with diazomethane, diazoethane and diazopropane to give products in good yield. Alantolactone, isoalantolactone and their derivatives prepared showed fairly good fungicidal activity against Alternaria brassicae, Rhizoctonia solani and Penicillium italicum. Indian Academy of Sciences, 2012 Alantolactone nationallicence isoalantolactone nationallicence fungitoxicity nationallicence Alternaria brassicae nationallicence Penicillium italicum nationallicence Rhizoctonia solani nationallicence KATARIA DALVIR Department of Chemistry, Punjab Agricultural University, 141 004, Ludhiana, India aut CHAHAL K. Department of Chemistry, Punjab Agricultural University, 141 004, Ludhiana, India aut Journal of Chemical Sciences Springer-Verlag 125/1(2013-01-01), 187-191 0974-3626 125:1<187 2013 125 12039 https://doi.org/10.1007/s12039-012-0347-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-012-0347-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- KATARIA DALVIR Department of Chemistry, Punjab Agricultural University, 141 004, Ludhiana, India aut NATIONALLICENCE 700 1- CHAHAL K. Department of Chemistry, Punjab Agricultural University, 141 004, Ludhiana, India aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer-Verlag 125/1(2013-01-01), 187-191 0974-3626 125:1<187 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer