naa a22 4500 510733301 CHVBK 20180411083000.0 cr unu---uuuuu 180411e20130101xx s 000 0 eng 10.1007/s12039-012-0355-9 doi (NATIONALLICENCE)springer-10.1007/s12039-012-0355-9 New bispyrazoline derivatives built around aliphatic chains: Synthesis, characterization and antimicrobial studies [Elektronische Daten] [MOHAMAD YUSUF, PAYAL JAIN] The bispyrazolines 3a-3h built around the alkyl chains of varying lengths have been synthesized from the cyclization reactions of bischalcones with phenyl hydrazine. The bischalcones 2a-2h were obtained from the Claisen-Schmidt reactions of acetophenone with various bisaldehydes 1a-1h. The intermediate bischalcones and final bisheterocyclic compounds have been characterized by means of IR, 1H-NMR, 13C-NMR, Mass (ESI) and elemental analysis. The antibacterial and antifungal activities of the synthesized compounds were also evaluated against the Klubsellia pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillius subtilis and Aspergillius janus, Aspergillus niger and Pencillium glabrum, respectively. The antimicrobial behaviour of the bispyrazolines 3a-3h is found to be dependent on the length of internal spacer unit. Graphical Abstract Synthesis and antimicrobial behaviour of the bispyrazolines built around the aliphatic chains have been described. The antimicrobial behaviour of these bisheterocyclic compounds is found to be dependent on the length of the internal spacer unit. Indian Academy of Sciences, 2013 Cyclization reactions nationallicence bischalcones nationallicence internal spacer nationallicence bispyrazolines nationallicence alkyl chains nationallicence antimicrobial activity nationallicence YUSUF MOHAMAD Department of Chemistry, Punjabi University, 147 002, Patiala, India aut JAIN PAYAL Department of Chemistry, Punjabi University, 147 002, Patiala, India aut Journal of Chemical Sciences Springer-Verlag 125/1(2013-01-01), 117-127 0974-3626 125:1<117 2013 125 12039 https://doi.org/10.1007/s12039-012-0355-9 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-012-0355-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- YUSUF MOHAMAD Department of Chemistry, Punjabi University, 147 002, Patiala, India aut NATIONALLICENCE 700 1- JAIN PAYAL Department of Chemistry, Punjabi University, 147 002, Patiala, India aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer-Verlag 125/1(2013-01-01), 117-127 0974-3626 125:1<117 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer