naa a22 4500 510733492 CHVBK 20180411083001.0 cr unu---uuuuu 180411e20130101xx s 000 0 eng 10.1007/s12039-012-0324-3 doi (NATIONALLICENCE)springer-10.1007/s12039-012-0324-3 Synthesis, photophysical property study of novel fluorescent 4-(1,3-benzoxazol-2-yl)-2-phenylnaphtho[1,2- d ][1,3]oxazole derivatives and their antimicrobial activity [Elektronische Daten] [KIRAN PHATANGARE, BHUSHAN BORSE, VIKAS PADALKAR, VIKAS PATIL, VINOD GUPTA, PRASHANT UMAPE, N SEKAR] A series of 4-(1,3-benzoxazol-2-yl)-2-phenylnaphtho[1,2-d][1,3]oxazole derivatives have been synthesized from intermediate 1-amino-3-(1,3-benzoxazol-2-yl)naphthalen-2-ol. This intermediate was obtained by coupling 3-(1,3-benzoxazol-2-yl)naphthalen-2-ol with 4-sulphobenzenediazonium chloride followed by reduction with sodium dithionate in water at pH 8-9. 3-(1,3-benzoxazol-2-yl)naphthalen-2-ol was synthesized from 3-hydroxynaphthalene-2-carboxylic acid and 2-amino phenol in the presence of PCl3 in chlorobenzene at 130-135°C. All these compounds were characterized by FT-IR, 1H NMR, mass spectral and elemental analysis. The synthesized compounds are fluorescent which absorbs in the range of 296 to 332nm while emits in the ranges of 368 to 404nm with excellent quantum yield. All compounds were evaluated for in vitro antibacterial activities against Escherichia coli and Staphylococcus aureus strains and in vitro antifungal activity against Candida albicans and Aspergillus niger strains by using serial dilution method. Graphical Abstract The structural analogues of UK-1 were synthesized by replacing one 1,3-benzoxazole ring by naphtho[1,2-d][1,3]oxazole ring. The synthesized compounds are fluorescent, absorb at 296-332 nm and emits at 368-404 nm. All compounds show good antifungal activity. Indian Academy of Sciences, 2013 Heterocyclic synthesis nationallicence benzoxazole nationallicence naphthoxazole nationallicence fluorescence nationallicence photophysical properties nationallicence antibacterial activity nationallicence antifungal activity nationallicence PHATANGARE KIRAN Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut BORSE BHUSHAN Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut PADALKAR VIKAS Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut PATIL VIKAS Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut GUPTA VINOD Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut UMAPE PRASHANT Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut SEKAR N. Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut Journal of Chemical Sciences Springer-Verlag 125/1(2013-01-01), 141-151 0974-3626 125:1<141 2013 125 12039 https://doi.org/10.1007/s12039-012-0324-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-012-0324-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- PHATANGARE KIRAN Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 700 1- BORSE BHUSHAN Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 700 1- PADALKAR VIKAS Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 700 1- PATIL VIKAS Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 700 1- GUPTA VINOD Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 700 1- UMAPE PRASHANT Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 700 1- SEKAR N. Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), NP Marg, Matunga, 400 019, Mumbai, India aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer-Verlag 125/1(2013-01-01), 141-151 0974-3626 125:1<141 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer