naa a22 4500 510733646 CHVBK 20180411083002.0 cr unu---uuuuu 180411e20131101xx s 000 0 eng 10.1007/s12039-013-0510-y doi (NATIONALLICENCE)springer-10.1007/s12039-013-0510-y Zn(OTf)2-catalysed indolylation and pyrrolylation of isatins: Efficient synthesis and biochemical assay of 3,3-di(heteroaryl)oxindoles [Elektronische Daten] [C PRAVEEN, S NARENDIRAN, P DHEENKUMAR, P PERUMAL] An efficient and cheap synthetic approach to 3,3-di(indolyl)oxindoles and 3,3-di(pyrrolyl)oxindoles has been developed via Zn(OTf)2 catalysed indolylation and pyrrolylation of isatins. A preliminary biochemical assay of the synthesized molecules in rodent models were performed to estimate the serum glutamate oxaloacetate transaminase and malondialdehyde levels. Graphical Abstract An efficient and cheap synthetic approach to 3,3-di(indolyl)oxindoles and 3,3- di(pyrrolyl)oxindoles has been developed via Zn(OTf)2-catalysed indolylation and pyrrolylation of isatins. A preliminary biochemical assay of the synthesized molecules in rodent models were performed to estimate the SGOT and MDA levels. Indian Academy of Sciences, 2013 Zn(OTf)2 nationallicence 3,3-di(indolyl)oxindoles nationallicence 3,3-di(pyrrolyl)oxindoles nationallicence serum glutamate oxaloacetate transaminase (SGOT) nationallicence malondialdehyde (MDA) nationallicence PRAVEEN C. Organic Chemistry ivision, Central Leather Research Institute (CSIR), Adyar, 600 020, Chennai, India aut NARENDIRAN S. Department of Pharmaceutical Chemistry, Sri Venkateswara College of Pharmacy, 517 127, Chitoor, India aut DHEENKUMAR P. Organic Chemistry ivision, Central Leather Research Institute (CSIR), Adyar, 600 020, Chennai, India aut PERUMAL P. Organic Chemistry ivision, Central Leather Research Institute (CSIR), Adyar, 600 020, Chennai, India aut Journal of Chemical Sciences Springer India 125/6(2013-11-01), 1543-1553 0974-3626 125:6<1543 2013 125 12039 https://doi.org/10.1007/s12039-013-0510-y text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-013-0510-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- PRAVEEN C. Organic Chemistry ivision, Central Leather Research Institute (CSIR), Adyar, 600 020, Chennai, India aut NATIONALLICENCE 700 1- NARENDIRAN S. Department of Pharmaceutical Chemistry, Sri Venkateswara College of Pharmacy, 517 127, Chitoor, India aut NATIONALLICENCE 700 1- DHEENKUMAR P. Organic Chemistry ivision, Central Leather Research Institute (CSIR), Adyar, 600 020, Chennai, India aut NATIONALLICENCE 700 1- PERUMAL P. Organic Chemistry ivision, Central Leather Research Institute (CSIR), Adyar, 600 020, Chennai, India aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer India 125/6(2013-11-01), 1543-1553 0974-3626 125:6<1543 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer