naa a22 4500 510734138 CHVBK 20180411083003.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s12039-013-0412-z doi (NATIONALLICENCE)springer-10.1007/s12039-013-0412-z Application of chalcones in heterocycles synthesis: Synthesis of 2-(isoxazolo, pyrazolo and pyrimido) substituted analogues of 1,4-benzodiazepin-5-carboxamides linked through an oxyphenyl bridge [Elektronische Daten] [N KAUR, D KISHORE] Versatility of chalcone derivative of 2-(4′-acetyl)-phenoxyl-5-carboxamido-1,4-benzodiazepin-5-(4′-methylpiperazinyl)-carboxamide (6) was explored to provide an easy one-pot access to its 2-(isoxazolo, pyrazolo and pyrimido) substituted analogues 9, 10, 11, 12, 13, 14, 15, and 16. Graphical Abstract An efficient novel strategy for the hetero-annulation of 2-chloro-1,4-benzodiazepine ring, substituted on its 5-position with a carboxamido group, has been developed to allow the incorporation of isoxazole, pyrazole and pyrimidine rings through their chalcone intermediate. Indian Academy of Sciences, 2013 1,4-Benzodiazepine nationallicence chalcone nationallicence isoxazole nationallicence pyrazole nationallicence pyrimidine nationallicence KAUR N. Department of Chemistry, Banasthali University, 304 022, Banasthali, India aut KISHORE D. Department of Chemistry, Banasthali University, 304 022, Banasthali, India aut Journal of Chemical Sciences Springer-Verlag 125/3(2013-05-01), 555-560 0974-3626 125:3<555 2013 125 12039 https://doi.org/10.1007/s12039-013-0412-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-013-0412-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- KAUR N. Department of Chemistry, Banasthali University, 304 022, Banasthali, India aut NATIONALLICENCE 700 1- KISHORE D. Department of Chemistry, Banasthali University, 304 022, Banasthali, India aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer-Verlag 125/3(2013-05-01), 555-560 0974-3626 125:3<555 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer