naa a22 4500 510734235 CHVBK 20180411083004.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s12039-013-0461-3 doi (NATIONALLICENCE)springer-10.1007/s12039-013-0461-3 Synthesis of novel N-, S-substituted-polyhalo-1, 3-butadienes and crystal structure of dibutadienyl homopiperazine [Elektronische Daten] [NAHIDE DENIZ, CEMIL IBIS] Polyhalogenated-2-nitro-1, 3-butadienes are important synthetic precursors for a variety of polyfunctionalized bioactive heterocycles. Herein, we report the reactions of 1, 1, 3, 4, 4-pentachloro-2-nitro-1, 3-butadiene 1 and 4-bromo-1, 1, 3, 4-tetrachloro-2-nitro-1, 3-butadiene 2 with amino and thiol containing nucleophiles to obtain highly functionalized (E)-polyhalodiene-2-nitro-1, 3-butadiene derivatives. Most of these reactions were found to be highly selective resulting in good to high yields of the products. All new compounds have been characterized by nuclear magnetic resonance spectroscopy (NMR), mass spectrometry (MS) and Fourier transform infrared spectroscopy (FT-IR) spectroscopic data. Single crystal X-ray structure analysis of compound 8c is reported. Graphical Abstract Polyhalogenated-2-nitro-1,3-butadienes are important synthetic precursors for a variety of polyfunctionalized bioactive heterocycles.We report here the reactions of 1,1,3,4,4-pentachloro-2-nitro-1,3-butadiene and 4-bromo-1,1,3,4-tetrachloro-2-nitro-1,3-butadiene with amino and thiol containing nucleophiles to obtain highly functionalized (E)-polyhalodiene-2-nitro-1,3-butadiene derivatives. All new compounds have been characterized by NMR, Mass and FT-IR. Indian Academy of Sciences, 2013 Piperazine nationallicence homopiperazine nationallicence thiomorpholine nationallicence 1, 3-butadiene nationallicence E -isomers nationallicence X-ray structure nationallicence DENIZ NAHIDE Engineering Faculty, Department of Chemistry, Division of Organic Chemistry, Istanbul University, Avcilar, Istanbul, Turkey aut IBIS CEMIL Engineering Faculty, Department of Chemistry, Division of Organic Chemistry, Istanbul University, Avcilar, Istanbul, Turkey aut Journal of Chemical Sciences Springer India 125/4(2013-07-01), 755-764 0974-3626 125:4<755 2013 125 12039 https://doi.org/10.1007/s12039-013-0461-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-013-0461-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- DENIZ NAHIDE Engineering Faculty, Department of Chemistry, Division of Organic Chemistry, Istanbul University, Avcilar, Istanbul, Turkey aut NATIONALLICENCE 700 1- IBIS CEMIL Engineering Faculty, Department of Chemistry, Division of Organic Chemistry, Istanbul University, Avcilar, Istanbul, Turkey aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer India 125/4(2013-07-01), 755-764 0974-3626 125:4<755 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer