naa a22 4500 510734480 CHVBK 20180411083004.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s12039-013-0450-6 doi (NATIONALLICENCE)springer-10.1007/s12039-013-0450-6 Efficient, green and solvent-free synthesis of tetrasubstituted imidazoles using SbCl3/SiO2 as heterogeneous catalyst [Elektronische Daten] [JAVAD SAFARI, SOHEILA GANDOMI-RAVANDI, SIMIN NASEH] Antimony trichloride absorbed on silica gel (SbCl3/SiO2) efficiently catalyses the four-component cyclocondensation of 1,2-diketone, aldehyde, ammonium acetate, and primary amine under solvent-free conditions to afford the corresponding tetrasubstituted imidazoles in high yields. The main merit of this study is introducing a novel catalyst to successful synthesis of a wide range of 1,2,4,5-tetrasubstituted imidazoles for the first time. The proposed method involves features such as simplicity, generality, fairly good efficiency, and reusability of the catalyst. Graphical Abstract An overall and effective synthetic strategy for the preparation of 1,2,4,5-tetrasubstituted imidazoles is introduced in the presence of SbCl3.SiO2 as a green and heterogeneous catalyst under solvent-free conditions. Indian Academy of Sciences, 2013 Imidazole nationallicence solvent-free conditions nationallicence four-component reaction nationallicence heterogeneous catalyst nationallicence Lewis acid nationallicence SAFARI JAVAD Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran aut GANDOMI-RAVANDI SOHEILA Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran aut NASEH SIMIN Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran aut Journal of Chemical Sciences Springer India 125/4(2013-07-01), 827-833 0974-3626 125:4<827 2013 125 12039 https://doi.org/10.1007/s12039-013-0450-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12039-013-0450-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- SAFARI JAVAD Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran aut NATIONALLICENCE 700 1- GANDOMI-RAVANDI SOHEILA Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran aut NATIONALLICENCE 700 1- NASEH SIMIN Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran aut NATIONALLICENCE 773 0- Journal of Chemical Sciences Springer India 125/4(2013-07-01), 827-833 0974-3626 125:4<827 2013 125 12039 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer