naa a22 4500 510735347 CHVBK 20180411083007.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11904-013-0164-x doi (NATIONALLICENCE)springer-10.1007/s11904-013-0164-x Transmission of Tuberculosis in Resource-Limited Settings [Elektronische Daten] [Tejaswi Kompala, Sheela Shenoi, Gerald Friedland] Unrecognized transmission is a major contributor to ongoing TB epidemics in high-burden, resource-constrained settings. Limitations in diagnosis, treatment, and infection control in health-care and community settings allow for continued transmission of drug-sensitive and drug-resistant TB, particularly in regions of high HIV prevalence. Health-care facilities are common sites of TB transmission. Improved implementation of infection control practices appropriate for the local setting and in combination, has been associated with reduced transmission. Community settings account for the majority of TB transmission and deserve increased focus. Strengthening and intensifying existing high-yield strategies, including household contact tracing, can reduce onward TB transmission. Recent studies documenting high transmission risk community sites and strategies for community-based intensive case finding hold promise for feasible, effective transmission reduction. Infection control in community settings has been neglected and requires urgent attention. Developing and implementing improved strategies for decreasing transmission to children, within prisons and of drug-resistant TB are needed. Springer Science+Business Media New York, 2013 Tuberculosis nationallicence Transmission nationallicence Resource-limited setting nationallicence South Africa nationallicence Infection control nationallicence Nosocomial nationallicence MDR/XDR TB nationallicence Ventilation nationallicence UV light nationallicence Household contact investigation nationallicence Health care workers nationallicence Intensive case finding nationallicence Community nationallicence HIV/TB co-infection nationallicence Kompala Tejaswi Boston University School of Medicine, 72 E. Concord Street, 02118, Boston, MA, USA aut Shenoi Sheela Yale University School of Medicine, 135 College Street, AIDS Suite 323, New Haven, CT, USA aut Friedland Gerald Yale University School of Medicine, 135 College Street, AIDS Suite 323, New Haven, CT, USA aut Current HIV/AIDS Reports Springer US; http://www.springer-ny.com 10/3(2013-09-01), 264-272 1548-3568 10:3<264 2013 10 11904 https://doi.org/10.1007/s11904-013-0164-x text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11904-013-0164-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kompala Tejaswi Boston University School of Medicine, 72 E. Concord Street, 02118, Boston, MA, USA aut NATIONALLICENCE 700 1- Shenoi Sheela Yale University School of Medicine, 135 College Street, AIDS Suite 323, New Haven, CT, USA aut NATIONALLICENCE 700 1- Friedland Gerald Yale University School of Medicine, 135 College Street, AIDS Suite 323, New Haven, CT, USA aut NATIONALLICENCE 773 0- Current HIV/AIDS Reports Springer US; http://www.springer-ny.com 10/3(2013-09-01), 264-272 1548-3568 10:3<264 2013 10 11904 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer