naa a22 4500 510735436 CHVBK 20180411083008.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s11904-013-0179-3 doi (NATIONALLICENCE)springer-10.1007/s11904-013-0179-3 Treatment Considerations for HIV-Infected Individuals with Severe Mental Illness [Elektronische Daten] [Michael Blank, Seth Himelhoch, James Walkup, Marlene Eisenberg] There has been a general recognition of a syndemic that includes HIV/AIDS and serve mental illnesses including schizophrenia, major depression, bipolar disorder, post-traumatic stress disorder, and others. The pathophysiology and direction of effects between severe mental illness and HIV infection is less clear however, and relatively little work has been done on prevention and treatment for people with these complex, co-occurring conditions. Here we present the most recent work that has been published on HIV and mental illness. Further, we describe the need for better treatments for "triply diagnosed persons”; those with HIV, mental illness, and substance abuse and dependence. Finally, we describe the potential drug-drug interactions between psychotropic medications and anti-retrovirals, and the need for better treatment guidelines in this area. We describe one example of an individually tailored intervention for persons with serious mental illness and HIV (PATH+) that shows that integrated community-based treatments using advanced practice nurses (APNs) as health navigators can be successful in improving health-related quality of life and reducing the burden of disease in these persons. Springer Science+Business Media New York, 2013 Syndemics nationallicence Severe mental illness nationallicence HIV nationallicence Substance abuse nationallicence Triply diagnosed nationallicence Drug-drug interactions nationallicence Treatment guidelines nationallicence Depression nationallicence Schizophrenia nationallicence Bipolar disorder nationallicence Anxiety disorder nationallicence PTSD nationallicence PATH+ nationallicence Blank Michael Center for Mental Health Policy and Services Research, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St., room 3020, 19104-3309, Philadelphia, PA, USA aut Himelhoch Seth Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, 701 W. Pratt Street, 388, Baltimore, MD, USA aut Walkup James Institute for Health, Health Care Policy and Aging Research, Rutgers, The State University of New Jersey, 112 Paterson, 08504, New Brunswick, NJ, USA aut Eisenberg Marlene Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St., Suite 4000, 19104, Philadelphia, PA, USA aut Current HIV/AIDS Reports Springer US; http://www.springer-ny.com 10/4(2013-12-01), 371-379 1548-3568 10:4<371 2013 10 11904 https://doi.org/10.1007/s11904-013-0179-3 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11904-013-0179-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Blank Michael Center for Mental Health Policy and Services Research, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St., room 3020, 19104-3309, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Himelhoch Seth Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, 701 W. Pratt Street, 388, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Walkup James Institute for Health, Health Care Policy and Aging Research, Rutgers, The State University of New Jersey, 112 Paterson, 08504, New Brunswick, NJ, USA aut NATIONALLICENCE 700 1- Eisenberg Marlene Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St., Suite 4000, 19104, Philadelphia, PA, USA aut NATIONALLICENCE 773 0- Current HIV/AIDS Reports Springer US; http://www.springer-ny.com 10/4(2013-12-01), 371-379 1548-3568 10:4<371 2013 10 11904 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer