naa a22 4500 510739075 CHVBK 20180411083021.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s12015-013-9461-4 doi (NATIONALLICENCE)springer-10.1007/s12015-013-9461-4 The Potential of Stem Cells in the Treatment of Cardiovascular Diseases [Elektronische Daten] [Aurora Bernal, Beatriz Gálvez] Although the adult mammalian heart was once believed to be a post-mitotic organ without any capacity for regeneration, recent findings have challenged this dogma. A modified view assigns to the mammalian heart a measurable capacity for regeneration throughout life. The ultimate goals of the cardiac regeneration field have been pursued by multiple strategies, including understanding the developmental biology of cardiomyocytes and cardiac stem and progenitor cells, applying chemical genetics, and engineering biomaterials and delivery methods that facilitate cell transplantation. Successful stimulation of endogenous regenerative capacity in injured adult mammalian hearts can benefit from studies of natural cardiac regeneration. The Author(s), 2013 Cardiac stem cells nationallicence Cardiac progenitors nationallicence Cardiomyocytes nationallicence Cardiac cell therapy nationallicence Bernal Aurora Centro Nacional de Investigaciones Cardiovasculares (CNIC), C/Melchor Fernández Almagro, 3, 28029, Madrid, Spain aut Gálvez Beatriz Centro Nacional de Investigaciones Cardiovasculares (CNIC), C/Melchor Fernández Almagro, 3, 28029, Madrid, Spain aut Stem Cell Reviews and Reports Springer US; http://www.springer-ny.com 9/6(2013-12-01), 814-832 1550-8943 9:6<814 2013 9 12015 https://doi.org/10.1007/s12015-013-9461-4 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12015-013-9461-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bernal Aurora Centro Nacional de Investigaciones Cardiovasculares (CNIC), C/Melchor Fernández Almagro, 3, 28029, Madrid, Spain aut NATIONALLICENCE 700 1- Gálvez Beatriz Centro Nacional de Investigaciones Cardiovasculares (CNIC), C/Melchor Fernández Almagro, 3, 28029, Madrid, Spain aut NATIONALLICENCE 773 0- Stem Cell Reviews and Reports Springer US; http://www.springer-ny.com 9/6(2013-12-01), 814-832 1550-8943 9:6<814 2013 9 12015 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer