naa a22 4500 510740537 CHVBK 20180411083026.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11845-013-0914-1 doi (NATIONALLICENCE)springer-10.1007/s11845-013-0914-1 The role of National Institutes of Health category IV prostatitis in accurately staging the newly diagnosed prostate cancer [Elektronische Daten] [E. Aglamis, C. Tasdemir, C. Ceylan] Background: It has been known that the National Institutes of Health category IV (NIH-IV) prostatitis increases the serum total prostate-specific antigen (tPSA) in patients with benign prostatic hyperplasia. However, the effect of NIH-IV prostatitis on tPSA levels, which are used for staging prostate cancer (PCa) in patients with PCa, has not been previously investigated. Aim: To evaluate the effect of NIH-IV prostatitis on the tPSA which is used for staging PCa in patients with newly diagnosed PCa. Method: A total of 198 patients in whom PCa was detected were included in the study. Group 1 included patients with only PCa, while Group 2 included patients with prostatitis and PCa. The tPSA levels of patients in Groups 1 and 2 were compared. Results: A total of 120 (61%) PCa (Group 1) and 78 (39%) PCa+NIH-IV prostatitis (Group 2) patients were identified. The tPSA levels of 70 (58%) patients in Group 1 and 22 (28%) patients in Group 2 were at the interval of <20ng/ml (the mean levels of tPSA: 11.8±4.5 and 14.1±3.3, respectively). The tPSA levels of 50 (42%) patients in Group 1 and 56 (72%) patients in Group 2 were within the range of ≥20ng/ml (the mean levels of tPSA: 39.9±31.0 and 47.0±29.2, respectively). Within both the <20ng/ml range and ≥20ng/ml range, the mean tPSA value in Group 2 was found to be significantly higher than that of Group 1 (p=0.03 and 0.01, respectively). Conclusion: The existence of NIH-IV prostatitis together with cancer in patients with PCa significantly increases the tPSA level which is used in staging the PCa. Royal Academy of Medicine in Ireland, 2013 Prostate cancer nationallicence Prostate-specific antigen nationallicence Prostatitis nationallicence Stage nationallicence Treatment nationallicence Biopsy nationallicence Aglamis E. Clinics of Urology, Elazig Education and Research Hospital, 23100, Elazig, Turkey aut Tasdemir C. Department of Urology, Inonu University Medical Faculty, Malatya, Turkey aut Ceylan C. Clinics of Urology, Turkey High Education and Research Hospital, Ankara, Turkey aut Irish Journal of Medical Science Springer-Verlag 182/3(2013-09-01), 463-467 0021-1265 182:3<463 2013 182 11845 https://doi.org/10.1007/s11845-013-0914-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11845-013-0914-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Aglamis E. Clinics of Urology, Elazig Education and Research Hospital, 23100, Elazig, Turkey aut NATIONALLICENCE 700 1- Tasdemir C. Department of Urology, Inonu University Medical Faculty, Malatya, Turkey aut NATIONALLICENCE 700 1- Ceylan C. Clinics of Urology, Turkey High Education and Research Hospital, Ankara, Turkey aut NATIONALLICENCE 773 0- Irish Journal of Medical Science Springer-Verlag 182/3(2013-09-01), 463-467 0021-1265 182:3<463 2013 182 11845 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer