naa a22 4500 510740855 CHVBK 20180411083027.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11845-013-0902-5 doi (NATIONALLICENCE)springer-10.1007/s11845-013-0902-5 Parkinson's disease: how is employment affected? [Elektronische Daten] [R. Murphy, N. Tubridy, H. Kevelighan, S. O'Riordan] Background: Rates of unemployment and early retirement are increased in Parkinson's disease (PD) and contribute to disease burden. Aims: To investigate time to loss of employment from PD onset and predictors of continued employment; to identify common issues and possible interventions in the workplace. Methods: Eighty-eight patients with PD diagnosed at age ≤65years took part in a retrospective cohort study. Veterans RAND Short Form-36 and an employment survey were administered. Results: Unemployment rates for males were increased compared to the general Irish population (standardized ratio of 1.6, 95% CI 1.2-2.2, P<0.05). There was no significant difference for females. Median retirement age was 58years for males and 61years for females compared to 63.5 and 65years, respectively, in the general population. In survival analysis, median time to loss of employment was 7years (95% CI 4.8-9.2). After 5years, 40% remained working and 14% after 10years. Early age of PD onset (P<0.001), early diagnosis (P<0.002) and high scores in vitality (P<0.005) were associated with prolonged employment. There was no association with sex, education, type or hours of work. Slowness, fatigue and tremor were the most challenging symptoms at work. Changes in work schedule and type of work were suggested helpful adjustments. Conclusion: Loss of employment places a significant socioeconomic burden on young PD patients. More detailed examination of specific issues and reasonable adjustments is needed, along with patient and employer education. Royal Academy of Medicine in Ireland, 2013 Parkinson's disease nationallicence Young nationallicence Socioeconomic nationallicence Financial nationallicence Employment nationallicence Murphy R. UCD School of Medicine and Medical Sciences, Belfield, Dublin 4, Ireland aut Tubridy N. Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland aut Kevelighan H. Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland aut O'Riordan S. Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland aut Irish Journal of Medical Science Springer-Verlag 182/3(2013-09-01), 415-419 0021-1265 182:3<415 2013 182 11845 https://doi.org/10.1007/s11845-013-0902-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11845-013-0902-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murphy R. UCD School of Medicine and Medical Sciences, Belfield, Dublin 4, Ireland aut NATIONALLICENCE 700 1- Tubridy N. Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland aut NATIONALLICENCE 700 1- Kevelighan H. Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland aut NATIONALLICENCE 700 1- O'Riordan S. Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland aut NATIONALLICENCE 773 0- Irish Journal of Medical Science Springer-Verlag 182/3(2013-09-01), 415-419 0021-1265 182:3<415 2013 182 11845 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer