naa a22 4500 510741053 CHVBK 20180411083028.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s11845-013-0935-9 doi (NATIONALLICENCE)springer-10.1007/s11845-013-0935-9 Comparison of prescribing and adherence patterns of anti-osteoporotic medications post-admission for fragility type fracture in an urban teaching hospital and a rural teaching hospital in Ireland between 2005 and 2008 [Elektronische Daten] [B. McGowan, K. Bennett, M. Casey, J. Doherty, C. Silke, B. Whelan] Introduction: Poor adherence reduces the potential benefits of osteoporosis therapy, lowering gains in bone mineral density resulting in increased risk of fractures. Aim: To compare prescribing and adherence patterns of anti-osteoporotic medications in patients admitted to an urban teaching hospital in Ireland with a fragility type fracture to patients admitted to a rural hospital in the North Western region. Methodology: We identified all patients >55years admitted to Sligo General Hospital between 2005 and 2008 with a fragility fracture (N=744) using the hospital in-patient enquiry system (HIPE). The medical card number of those patients eligible for the primary care reimbursement services scheme (PCRS) facilitated the linkage of the HSE-PCRS scheme database to the HIPE database which enabled a study to identify persistence rates of patients prescribed osteoporosis therapy after discharge. The results were compared to the findings of a similar study carried out in St. James's Hospital, Dublin. Results: The 12months post-fracture prescribing increased from 11.0% (95% CI 9.6, 12.4) in 2005 to 47% (95% CI 43.6, 50.3) in 2008 in the urban setting and from 25% (95% CI 21.5, 28.9) to 39% (95% CI 34.5, 42.7) in the rural setting. Adherence levels to osteoporosis medications at 12months post-initiation of therapy was <50% in both study groups. Patients on less frequent dosing regimes were better adherers. Conclusion: The proportion of patients being discharged on anti-osteoporosis medications post-fragility fracture increased between 2005 and 2008 in both patient groups. Sub-optimal adherence levels to osteoporosis medications continue to be a major concern. Royal Academy of Medicine in Ireland, 2013 Osteoporosis nationallicence Prescribing nationallicence Fragility fractures nationallicence Linkage nationallicence Datasets nationallicence Persistence nationallicence McGowan B. The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co Leitrim, Ireland aut Bennett K. Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland aut Casey M. Osteoporosis and Bone Health Clinic, Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland aut Doherty J. Osteoporosis and Bone Health Clinic, Medicine for the Elderly, Sligo Regional Hospital, Sligo, Ireland aut Silke C. The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co Leitrim, Ireland aut Whelan B. The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co Leitrim, Ireland aut Irish Journal of Medical Science Springer London 182/4(2013-12-01), 601-608 0021-1265 182:4<601 2013 182 11845 https://doi.org/10.1007/s11845-013-0935-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11845-013-0935-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McGowan B. The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co Leitrim, Ireland aut NATIONALLICENCE 700 1- Bennett K. Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland aut NATIONALLICENCE 700 1- Casey M. Osteoporosis and Bone Health Clinic, Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland aut NATIONALLICENCE 700 1- Doherty J. Osteoporosis and Bone Health Clinic, Medicine for the Elderly, Sligo Regional Hospital, Sligo, Ireland aut NATIONALLICENCE 700 1- Silke C. The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co Leitrim, Ireland aut NATIONALLICENCE 700 1- Whelan B. The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co Leitrim, Ireland aut NATIONALLICENCE 773 0- Irish Journal of Medical Science Springer London 182/4(2013-12-01), 601-608 0021-1265 182:4<601 2013 182 11845 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer