naa a22 4500 510741320 CHVBK 20180411083029.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s11845-013-0959-1 doi (NATIONALLICENCE)springer-10.1007/s11845-013-0959-1 A retrospective audit of 200 cases of CNS tumours and their surgical management in a tertiary care centre [Elektronische Daten] [F. Muhamat Nor, K. Chandrasekaran, J. Marks] Aims: To study the nature of the tumours managed in the Irish population. Methods: This audit research was completed via a retrospective medical review on 200 patients with CNS tumours managed in a tertiary care centre between 2008 and 2009. Results: The mean age was 53years. The male:female ratio was 2:1. The majority were glioblastomas and astrocytomas. Grade IV tumours were predominant (65.5%). Headaches (37%), motor weakness (32%) and seizures (25.5%) were the highest presentations. The commonest sites affected were the left parietal and left temporal lobes. There were 17.5% operative morbidities with motor weakness (22.9%), seizure (14.3%) and thrombo-embolism (14.3%) dominating and significant association to surgical radicality (p=0.041). 3.5% operative mortalities were reported. 52.5 and 62.5% of patients received adjuvant chemotherapy and radiotherapy, respectively. Conclusions: Patients with CNS tumours typically had multiple presentations. More extensive surgical resection was associated with higher postoperative morbidities (p=0.041). The 30-day postoperative morbidity (17.5%) and mortality (3.5%) were concordant with the currently available literature. Royal Academy of Medicine in Ireland, 2013 Central nervous system tumours nationallicence Operative mortality nationallicence Operative morbidity nationallicence Presenting features nationallicence Cork University Hospital nationallicence Neurosurgery nationallicence Muhamat Nor F. Department of Neurosurgery, Cork University Hospital, Wilton, Cork, Republic of Ireland aut Chandrasekaran K. Department of Neurosurgery, Cork University Hospital, Wilton, Cork, Republic of Ireland aut Marks J. Department of Neurosurgery, Cork University Hospital, Wilton, Cork, Republic of Ireland aut Irish Journal of Medical Science Springer London 182/4(2013-12-01), 697-701 0021-1265 182:4<697 2013 182 11845 https://doi.org/10.1007/s11845-013-0959-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11845-013-0959-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Muhamat Nor F. Department of Neurosurgery, Cork University Hospital, Wilton, Cork, Republic of Ireland aut NATIONALLICENCE 700 1- Chandrasekaran K. Department of Neurosurgery, Cork University Hospital, Wilton, Cork, Republic of Ireland aut NATIONALLICENCE 700 1- Marks J. Department of Neurosurgery, Cork University Hospital, Wilton, Cork, Republic of Ireland aut NATIONALLICENCE 773 0- Irish Journal of Medical Science Springer London 182/4(2013-12-01), 697-701 0021-1265 182:4<697 2013 182 11845 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer