naa a22 4500 510743471 CHVBK 20180411083036.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s12630-013-0044-2 doi (NATIONALLICENCE)springer-10.1007/s12630-013-0044-2 New supraglottic airway with built-in pressure indicator decreases postoperative pharyngolaryngeal symptoms: a randomized controlled trial [Elektronische Daten] [David Wong, Amanda Tam, Vanita Mehta, Raviraj Raveendran, Waleed Riad, Frances Chung] Un nouveau dispositif supraglottique avec un indicateur intégré de pression diminue les symptômes pharyngo-laryngés postopératoires: un essai randomisé contrôlé Purpose: Excessive supraglottic airway cuff pressure increases postoperative pharyngolaryngeal symptoms such as sore throat, dysphonia, and dysphagia. A new supraglottic airway, AES Ultra CPV™ (CPV), has a built-in intracuff pressure indicator. We hypothesized that using the CPV would reduce postoperative symptoms when compared with the LMA Classic™ (LMA) without intracuff pressure guidance. Methods: Ambulatory patients undergoing general anesthesia were randomized to either CPV or LMA. A size 3/4/5 was inserted according to manufacturer guidelines. Nitrous oxide was not used. In the LMA Group, the cuff was inflated according to manufacturer's guidelines. In the CPV Group, a CPV was inserted and the cuff inflated until the indicator was in the green zone (30-44mmHg). Intracuff pressures were measured at five minutes and 20min post-insertion in both groups. The primary outcome was the incidence of pharyngolaryngeal symptoms, defined as sore throat, dysphonia, and/or dysphagia at one, two, and/or 24hr postoperatively. Continuous data were compared using Student's t test and categorical data were analyzed using Chi square analysis. Results: The study included 170 patients, 85 per group. The mean (SD) intracuff pressure in the CPV group was significantly lower [44 (4) mmHg] than in the LMA Group [87 (37) mmHg]; P<0.001. The incidence of pharyngolaryngeal symptoms was significantly lower in the CPV Group than in the LMA Group (26% vs 49%; P=0.002). The absolute risk reduction was 24%, and the number-needed-to-treat was 4.3. Conclusion: The incidence of postoperative pharyngolaryngeal symptoms in the CPV Group with a cuff pressure-guided strategy was significantly lower than in the LMA Group with standard practice. (Clinical trial registration number: NCT01800344). Canadian Anesthesiologists' Society, 2013 Wong David Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut Tam Amanda College of Biological Science, University of Guelph, Guelph, ON, Canada aut Mehta Vanita Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut Raveendran Raviraj Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut Riad Waleed Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut Chung Frances Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut Canadian Journal of Anesthesia/Journal canadien d'anesthésie Springer US; http://www.springer-ny.com 60/12(2013-12-01), 1197-1203 0832-610X 60:12<1197 2013 60 12630 https://doi.org/10.1007/s12630-013-0044-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12630-013-0044-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wong David Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Tam Amanda College of Biological Science, University of Guelph, Guelph, ON, Canada aut NATIONALLICENCE 700 1- Mehta Vanita Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Raveendran Raviraj Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Riad Waleed Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Chung Frances Department of Anesthesia, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, M5T 2S8, Toronto, ON, Canada aut NATIONALLICENCE 773 0- Canadian Journal of Anesthesia/Journal canadien d'anesthésie Springer US; http://www.springer-ny.com 60/12(2013-12-01), 1197-1203 0832-610X 60:12<1197 2013 60 12630 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer