naa a22 4500 510746144 CHVBK 20180411083046.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s12192-013-0403-5 doi (NATIONALLICENCE)springer-10.1007/s12192-013-0403-5 Serum levels of heat shock protein 27 in patients with acute ischemic stroke [Elektronische Daten] [Gabriella Gruden, Federica Barutta, Irene Catto, Giovanni Bosco, Maria Caprioli, Silvia Pinach, Paolo Fornengo, Paolo Cavallo-Perin, Ottavio Davini, Paolo Cerrato, Graziella Bruno] Expression of intracellular heat shock protein 27 (Hsp27) rises in the brain of animal models of cerebral ischemia and stroke. Hsp27 is also released into the circulation and the aim of the present study was to investigated if serum Hsp27 (sHsp27) levels are altered in patients with acute ischemic stroke. sHsp27 was measured in 15 patients with acute ischemic stroke and in 14 control subjects comparable for age, sex, and cardiovascular risk factors. In patients, measurements were performed at admission and 1, 2, and 30days thereafter. At admission, mean sHsp27 values were threefold higher in patients than in controls. In patients, sHsp27 values dropped after 24h, rose again at 48h, and markedly declined at 30days, indicating the presence of a temporal trend of sHsp27 values following acute ischemic stroke. Cell Stress Society International, 2013 Acute ischemic stroke nationallicence Heat shock protein 27 nationallicence Serum biomarker nationallicence Stress response nationallicence Gruden Gabriella Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Barutta Federica Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Catto Irene Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Bosco Giovanni Stroke Unit, San Giovanni Battista Hospital, Turin, Italy aut Caprioli Maria Stroke Unit, San Giovanni Battista Hospital, Turin, Italy aut Pinach Silvia Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Fornengo Paolo Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Cavallo-Perin Paolo Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Davini Ottavio Radiology 2 - San Giovanni Battista Hospital, Turin, Italy aut Cerrato Paolo Stroke Unit, San Giovanni Battista Hospital, Turin, Italy aut Bruno Graziella Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut Cell Stress and Chaperones Springer Netherlands 18/4(2013-07-01), 531-533 1355-8145 18:4<531 2013 18 12192 https://doi.org/10.1007/s12192-013-0403-5 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12192-013-0403-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gruden Gabriella Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 700 1- Barutta Federica Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 700 1- Catto Irene Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 700 1- Bosco Giovanni Stroke Unit, San Giovanni Battista Hospital, Turin, Italy aut NATIONALLICENCE 700 1- Caprioli Maria Stroke Unit, San Giovanni Battista Hospital, Turin, Italy aut NATIONALLICENCE 700 1- Pinach Silvia Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 700 1- Fornengo Paolo Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 700 1- Cavallo-Perin Paolo Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 700 1- Davini Ottavio Radiology 2 - San Giovanni Battista Hospital, Turin, Italy aut NATIONALLICENCE 700 1- Cerrato Paolo Stroke Unit, San Giovanni Battista Hospital, Turin, Italy aut NATIONALLICENCE 700 1- Bruno Graziella Department of Medical Science, University of Turin, C/so Dogliotti 14, 10126, Turin, Italy aut NATIONALLICENCE 773 0- Cell Stress and Chaperones Springer Netherlands 18/4(2013-07-01), 531-533 1355-8145 18:4<531 2013 18 12192 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer