naa a22 4500 510747213 CHVBK 20180411083050.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11547-013-0946-7 doi (NATIONALLICENCE)springer-10.1007/s11547-013-0946-7 Whole-body MRI and PET/CT in multiple myeloma patients during staging and after treatment: personal experience in a longitudinal study [Elektronische Daten] [Giuseppe Cascini, Carmela Falcone, Domenico Console, Antonino Restuccia, Marco Rossi, Antonello Parlati, Oscar Tamburrini] Risonanza magnetica whole body e TC/PET in pazienti con mieloma multiplo in stadiazione e dopo trattamento: esperienza personale in uno studio longitudinale Purpose: Diagnostic imaging plays a pivotal role in staging and prognostic assessment of multiple myeloma (MM) as well as planning and monitoring treatment. The aim of our study was to estimate the diagnostic accuracy of wholebody magnetic resonance imaging (WB-MRI) and positron emission tomography/computed tomography (PET/CT) in MM patients studied before and after treatment. Materials and methods: We considered 22 consecutive patients (10 males, 12 females; age range, 48-83 years) with newly diagnosed MM (NDMM group), and the same 22 patients underwent at least one re-assessment after treatment (previously treated MM, PTMM group). WBMRI and PET/CT were performed within days from each other in both the NDMM (22 studies) and PTMM (29 studies) group. The imaging findings were compared to the results of bone marrow aspiration. Results: PET/CT was positive in 18/22 NDMM patients, whereas WB-MRI correctly identified 100% of patients. Of 20 responder patients in the PTMM group, 16 were negative at PET/CT and 12/20 at MRI. By contrast, of the nine nonresponder patients, MRI correctly detected active disease in all cases, and PET only in seven. Conclusions: WB-MRI proved superior to PET/CT in detecting MM, especially in diffuse disease. PET/CT appears to be more sensitive in the assessment of MM after treatment. Springer-Verlag Italia, 2013 WB-MRI nationallicence PET/CT nationallicence Multiple myeloma nationallicence Whole-body imaging nationallicence WB-RM nationallicence TC/PET nationallicence Mieloma multiplo nationallicence Imaging whole body nationallicence Cascini Giuseppe U.O.C. Medicina Nucleare, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia Catanzaro, Catanzaro, Italy aut Falcone Carmela U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut Console Domenico U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut Restuccia Antonino U.O.C. Medicina Nucleare, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia Catanzaro, Catanzaro, Italy aut Rossi Marco U.O.C. Oncologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut Parlati Antonello U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut Tamburrini Oscar U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut La radiologia medica Springer Milan 118/6(2013-09-01), 930-948 0033-8362 118:6<930 2013 118 11547 https://doi.org/10.1007/s11547-013-0946-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-013-0946-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cascini Giuseppe U.O.C. Medicina Nucleare, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia Catanzaro, Catanzaro, Italy aut NATIONALLICENCE 700 1- Falcone Carmela U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut NATIONALLICENCE 700 1- Console Domenico U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut NATIONALLICENCE 700 1- Restuccia Antonino U.O.C. Medicina Nucleare, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia Catanzaro, Catanzaro, Italy aut NATIONALLICENCE 700 1- Rossi Marco U.O.C. Oncologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut NATIONALLICENCE 700 1- Parlati Antonello U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut NATIONALLICENCE 700 1- Tamburrini Oscar U.O.C. Radiologia, Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/6(2013-09-01), 930-948 0033-8362 118:6<930 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer