naa a22 4500 510747396 CHVBK 20180411083051.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s11547-013-0929-8 doi (NATIONALLICENCE)springer-10.1007/s11547-013-0929-8 Oedema of gallbladder wall: correlation with chronic hepatitis B on MR imaging [Elektronische Daten] [Jian Shu, Jian Zhao, Fu Han, Guang Tang, Yin Luo, Xin Chen, Li Luo] Edema della colecisti: correlazione con l'epatite B cronica all'imaging RM Purpose: The aim of this study was to characterise gallbladder wall oedema and correlate it with chronic hepatitis B (CHB) on magnetic resonance (MR) imaging. Materials and methods: Sixty-seven patients who were clinically and histologically diagnosed with CHB and 18 healthy individuals without any history of liver disease underwent abdominal MR imaging. Hepatic inflammation (grade 0-4) and fibrosis (stage 0-4) for patients were assessed histologically. Gallbladder wall oedema was noted. Results: Twelve patients showed gallbladder wall oedema on MR imaging, including six with grade 3 and six with grade 4 disease. There was a statistically significant difference for the presence of gallbladder wall oedema among groups with grade 0-4 (p=0.000), but not between groups with grades 3 and 4 (p=0.729). Gallbladder wall oedema was related to moderate-severe inflammatory activity (p<0.05), alanine transaminase (ALT) (p=0.012) and aspartate aminotransferase (AST) (p=0.027) levels but not to fibrosis or other laboratory data, including serum quantitative DNA for hepatitis B virus (HBV), with the p=0.105-0.846. Sensitivity and specificity for the diagnosis of hepatic moderate-severe inflammation using gallbladder wall oedema were 33.33% and 100%, respectively. Conclusions: Gallbladder wall oedema for patients with CHB can be specifically demonstrated on MR imaging and is correlated with hepatic moderate-severe inflammatory activity, elevated ALT and AST levels but not with fibrosis or other laboratory data, including viremia. Springer-Verlag, 2013 Chronic hepatitis B nationallicence Magnetic resonance imaging nationallicence Gallbladder wall oedema nationallicence Inflammation nationallicence Epatite B cronica nationallicence Imaging con risonanza magnetica nationallicence Edema della parete colecistica nationallicence Infiammazione nationallicence Shu Jian Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut Zhao Jian Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, 400010, Chongqing, People's Republic of China aut Han Fu Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut Tang Guang Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut Luo Yin Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, 400010, Chongqing, People's Republic of China aut Chen Xin Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut Luo Li Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut La radiologia medica Springer-Verlag 118/7(2013-10-01), 1102-1108 0033-8362 118:7<1102 2013 118 11547 https://doi.org/10.1007/s11547-013-0929-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-013-0929-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shu Jian Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut NATIONALLICENCE 700 1- Zhao Jian Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, 400010, Chongqing, People's Republic of China aut NATIONALLICENCE 700 1- Han Fu Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut NATIONALLICENCE 700 1- Tang Guang Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut NATIONALLICENCE 700 1- Luo Yin Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, 400010, Chongqing, People's Republic of China aut NATIONALLICENCE 700 1- Chen Xin Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut NATIONALLICENCE 700 1- Luo Li Department of Radiology, Affiliated Hospital of Luzhou Medical College, 646000, Luzhou, Sichuan, People's Republic of China aut NATIONALLICENCE 773 0- La radiologia medica Springer-Verlag 118/7(2013-10-01), 1102-1108 0033-8362 118:7<1102 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer