naa a22 4500 510747574 CHVBK 20180411083052.0 cr unu---uuuuu 180411e20130401xx s 000 0 eng 10.1007/s11547-012-0873-z doi (NATIONALLICENCE)springer-10.1007/s11547-012-0873-z Accuracy of visual analysis vs. apparent diffusion coefficient quantification in differentiating solid benign and malignant focal liver lesions with diffusion-weighted imaging [Elektronische Daten] [R. Girometti, M. Del Pin, S. Pullini, L. Cereser, G. Como, M. Bazzocchi, C. Zuiani] Accuratezza dell'analisi visiva vs. la quantificazione del coefficiente di diffusione apparente nella differenziazione con imaging pesato in diffusione fra lesioni focali epatiche benigne solide e maligne Purpose: The authors compared the accuracy of diffusion-weighted imaging (DWI) visual analysis (VA) vs. apparent diffusion coefficient quantification (ADC-Q) in assessing malignancy of solid focal liver lesions (FLLs). Materials and methods: Using a 1.5-T system, two radiologists retrospectively assessed as benign or malignant 50 solid FLLs: (a) by VA of signal intensity on DWI images at b=800 s/mm2 and ADC map; (b) by quantifying lesion ADC. Reference standard included histology or follow-up confirmation of diagnosis by a consensus panel. Receiver operating characteristic (ROC) curve analysis was performed. Results Because of 20 false-negative hepatocellular carcinomas, VA showed lower accuracy than ADC-Q (52.0% vs. 68.0%). However, stratified accuracy for metastases was higher with VA (75.0 vs. 66%). ADC and signal features of malignant and benign FLLs were found to largely overlap: Conclusions: VA performed worse than ADC-Q for hepatocellular carcinoma and better for metastases. Overall, the accuracy of both methods was limited because of the overlap in visual appearance and ADC values between solid benign and malignant FLLs. Springer-Verlag Italia, 2012 Diffusion-weighted imaging nationallicence Visual analysis nationallicence Apparent diffusion coefficient nationallicence Focal liver lesions nationallicence Accuracy nationallicence Imaging pesato in diffusione nationallicence Analisi visiva nationallicence Coefficiente di diffusione apparente nationallicence Lesioni focali epatiche nationallicence Accuratezza nationallicence Girometti R. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut Del Pin M. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut Pullini S. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut Cereser L. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut Como G. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut Bazzocchi M. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut Zuiani C. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut La radiologia medica Springer Milan 118/3(2013-04-01), 343-355 0033-8362 118:3<343 2013 118 11547 https://doi.org/10.1007/s11547-012-0873-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0873-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Girometti R. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Del Pin M. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Pullini S. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Cereser L. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Como G. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Bazzocchi M. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Zuiani C. Institute of Diagnostic Radiology, University of Udine, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia”, Via Colugna 50, 33100, Udine, Italy aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/3(2013-04-01), 343-355 0033-8362 118:3<343 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer