naa a22 4500 510747639 CHVBK 20180411083052.0 cr unu---uuuuu 180411e20130401xx s 000 0 eng 10.1007/s11547-012-0860-4 doi (NATIONALLICENCE)springer-10.1007/s11547-012-0860-4 Recurrence in giant cell tumour of bone: imaging features and risk factors [Elektronische Daten] [Cheng-Sheng Wang, Jiang-Hua Lou, Jin-Sheng Liao, Xiao-Yi Ding, Lian-Jun Du, Yong Lu, Ling Yan, Ke-Min Chen] Tumore osseo a cellule giganti recidivante: caratteristiche radiologiche e fattori di rischio Purpose: This study was done to investigate X-ray, computed tomography (CT) and magnetic resonance (MR) imaging features of recurrence in giant cell tumour of bone (GCTB) and to evaluate risk factors. Materials and methods: Medical records and imaging data were reviewed for 55 cases of recurrent GCTB. All images were reviewed retrospectively and independently by two radiologists experienced in skeletal musculature. The common radiological findings; factors related to tumour recurrence such as gender, age, location; pathological fracture, Campanacci grading and surgical procedure were analysed by nonparametric test (Mann-Whitney U test for two independent samples test and Kruskal-Wallis H test for multiple independent samples test). p values <0.05 were considered to indicate a statistically significant difference. Results: The imaging features of recurrent GCTB were as follows: osteolytic destruction or bone resorption of graft bone or around the polymethylmethacrylate (PMMA), soft tissue mass formation and expansile change. Tumour parenchyma showed markedly heterogeneous enhancement, except for necrotic cystic cavities, on contrast-enhanced MR images. Wide resection had a smaller (p=0.031) risk of local recurrence than did intralesional curettage. There was no statistical significance in gender, age, location, pathological fracture and Campanacci staging (p>0.05). Conclusions: The risk of recurrence in GCTB was influenced by the type of surgery and adjuvants. Bone transformaresorption, soft tissue mass formation and aggravated expansile change are reliable signs of recurrence on imaging. Springer-Verlag Italia, 2012 Bone neoplasms nationallicence Giant cell tumours nationallicence Recurrence nationallicence Computed tomography nationallicence X-rays nationallicence Magnetic resonance imaging nationallicence Neoplasie ossee nationallicence Tumore a cellule giganti nationallicence Recidiva nationallicence Tomografia computerizzata nationallicence Radiografia nationallicence Risonanza magnetica nationallicence Wang Cheng-Sheng Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Lou Jiang-Hua Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Liao Jin-Sheng Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Ding Xiao-Yi Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Du Lian-Jun Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Lu Yong Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Yan Ling Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut Chen Ke-Min Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut La radiologia medica Springer Milan 118/3(2013-04-01), 456-464 0033-8362 118:3<456 2013 118 11547 https://doi.org/10.1007/s11547-012-0860-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0860-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Cheng-Sheng Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Lou Jiang-Hua Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Liao Jin-Sheng Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Ding Xiao-Yi Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Du Lian-Jun Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Lu Yong Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Yan Ling Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 700 1- Chen Ke-Min Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin 2nd Road, 200025, Shanghai, China aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/3(2013-04-01), 456-464 0033-8362 118:3<456 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer