naa a22 4500 510747760 CHVBK 20180411083053.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s11547-012-0890-x doi (NATIONALLICENCE)springer-10.1007/s11547-012-0890-x Nasopharyngeal carcinoma: correlation of apparent diffusion coefficient value with prognostic parameters [Elektronische Daten] [Ahmed Abdel Razek, Elsharawey Kamal] Carcinoma nasofaringeo: correlazione tra il valore del coefficiente apparente di diffusione e i parametri prognostici Purpose: The aim of this study was to correlate the apparent diffusion coefficient (ADC) value with the prognostic parameters of nasopharyngeal carcinoma (NPC). Materials and methods: This was a prospective study conducted on 30 consecutive patients (19 men, 11 women; mean age 61 years) with NPC. Patients underwent diffusion-weighted magnetic resonance (DW-MR) singleshot echoplanar imaging at 1.5 Tesla. NPC ADC value was correlated with pathological tumour type, pathological tumour grade, tumour volume and nodal status. Results: Mean NPC ADC value was 0.99±0.11×10−3mm2/s. ADC values of well-differentiated and moderately differentiated tumours differed significantly (p=0.005) from those of poorly differentiated and undifferentiated NPC. There was also a significant difference in ADC value among small, medium and large tumour volume (p=0.03). ADC value was also significantly lower (p=0.003) when metastatic cervical lymph nodes were present. ADC value correlated inversely with tumour volume (r=−0.799, p=0.03). Conclusions: ADC value can be considered a noninvasive prognostic parameter that correlates well with prognostic parameters of NPC. Springer-Verlag Italia, 2012 Diffusion nationallicence Nasopharynx nationallicence Carcinoma nationallicence MR imaging nationallicence Diffusione nationallicence Nasofaringe nationallicence Carcinoma nationallicence RM nationallicence Abdel Razek Ahmed Department of Radiology, Mansoura Faculty of Medicine, 13351, Mansoura, Egypt aut Kamal Elsharawey Department of ENT and Head and Neck Surgery, Mansoura Faculty of Medicine, Mansoura, Egypt aut La radiologia medica Springer Milan 118/4(2013-06-01), 534-539 0033-8362 118:4<534 2013 118 11547 https://doi.org/10.1007/s11547-012-0890-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0890-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Abdel Razek Ahmed Department of Radiology, Mansoura Faculty of Medicine, 13351, Mansoura, Egypt aut NATIONALLICENCE 700 1- Kamal Elsharawey Department of ENT and Head and Neck Surgery, Mansoura Faculty of Medicine, Mansoura, Egypt aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/4(2013-06-01), 534-539 0033-8362 118:4<534 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer