naa a22 4500 510747817 CHVBK 20180411083053.0 cr unu---uuuuu 180411e20130601xx s 000 0 ita 10.1007/s11547-012-0903-x doi (NATIONALLICENCE)springer-10.1007/s11547-012-0903-x Studio elastografico quantitativo mediante "supersonic shear imaging” nella diagnosi del tumore alla mammella [Elektronische Daten] [Zhi Wang, Jun Li, Min Li, Yan Huang, Wen Wan, Jie Tang] Study of quantitative elastography with supersonic shear imaging in the diagnosis of breast tumours Purpose: This study was undertaken to evaluate the value of quantitative elastography in the diagnosis of breast tumours. Materials and methods: Conventional ultrasound (US) and quantitative elastography were performed in 108 women with 114 breast lesions by two experienced radiologists, and pathological results were available in all cases. For each lesion, the maximum, mean, and minimum (min) elasticity and elasticity ratio between lesions and surrounding tissue were measured. The Breast Imaging Reporting and Data System (BI-RADS) categories were assessed with conventional US in all lesions. Results: Malignant lesions exhibited significantly higher maximum and mean elasticity (111.57±69.29 kPa and 54.49±33.70 kPa) than did benign lesions (59.00±45.3 kPa and 36.64±26.18 kPa) (p<0.01). For maximum elasticity versus BI-RADS, performance results were sensitivity 60.9 % vs. 78.3%, specificity 85.3% vs. 98.5%, positive predictive value (PPV) 73.7% vs. 97.3 %, negative predictive value (NPV) 76.3% vs. 87.0 % and accuracy 75.4% vs. 90.3%. BI-RADS had significantly better accuracy than maximum elasticity (p<0.01). Maximum and mean elasticity of invasive ductal carcinoma (IDC) were significantly higher than those of fibroadenoma (p<0.01), whereas the difference was not statistically significant with fibroadenosis, papilloma and inflammation (p>0.01). Maximum and mean elasticity and elasticity ratio of BI-RADS 5 were all significantly higher than those of BI-RADS 3 (p<0.01). Reliability for maximum and mean elasticity were almost perfect [intraclass correlation coefficients (ICC)=0.87 and 0.79]. Conclusions: Shear-wave elastography gives quantitative elasticity information that could potentially help in breast-lesion characterisation, although it cannot replace conventional BI-RADS in the differentiation of breast lesions. Springer-Verlag Italia, 2012 Breast neoplasms nationallicence Ultrasonography nationallicence Shearwave elastography nationallicence Diagnosis nationallicence Quantitative analysis nationallicence Tumore della mammella nationallicence Ecografia nationallicence Shear-wave elastografia nationallicence Diagnosi nationallicence Analisi quantitativa nationallicence Wang Zhi Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut Li Jun Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut Li Min Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut Huang Yan Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut Wan Wen Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut Tang Jie Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut La radiologia medica Springer Milan 118/4(2013-06-01), 583-590 0033-8362 118:4<583 2013 118 11547 https://doi.org/10.1007/s11547-012-0903-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0903-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Zhi Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut NATIONALLICENCE 700 1- Li Jun Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut NATIONALLICENCE 700 1- Li Min Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut NATIONALLICENCE 700 1- Huang Yan Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut NATIONALLICENCE 700 1- Wan Wen Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut NATIONALLICENCE 700 1- Tang Jie Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, 100853, Beijing, China aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/4(2013-06-01), 583-590 0033-8362 118:4<583 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer