naa a22 4500 510747892 CHVBK 20180411083053.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s11547-012-0871-1 doi (NATIONALLICENCE)springer-10.1007/s11547-012-0871-1 Evaluation of intracranial aneurysms with high-resolution MR angiography using single-artery highlighting technique: correlation with digital subtraction angiography [Elektronische Daten] [Hui Li, Lei Yan, Ming-Hua Li, Yong-Dong Li, Hua-Qiao Tan, Bin-Xian Gu, Wu Wang] Valutazione degli aneurismi intracranici mediante angio-RM ad alta risoluzione attraverso la tecnica single-artery highlighting:correlazione con angiografia con sottrazione digitale Purpose: The authors investigated the effectiveness of high-resolution magnetic resonance angiography (MRA) using a single-artery highlighting technique for the accurate diagnosis of intracranial aneurysms at 3.0 T in a large cohort of patients with suspected intracranial aneurysms against the current gold standard, i.e. cerebral angiography. Methods: A total of 307 patients with suspected aneurysms were referred for three-dimensional time-of-flight MRA (3D-TOF-MRA) prior to digital subtraction angiography (DSA). We summarised patient-based, aneurysm-based and vessel-based diagnostic performance parameters, namely, accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for detecting intracranial aneurysms with 3D-TOF-MRA. Interobserver agreement was calculated with the kappa (κ) statistic. Results: Patient-based accuracy was 98.1%, sensitivity 99.5%, specificity 95.3%, PPV 97.6% and NPV 99% according to observer A; and 97.7%, 99.5%, 94.3%, 97.1% and 99%, respectively, according to observer B. Aneurysmbased accuracy was 98.3%, sensitivity 99.6%, specificity 95.2%, PPV 98.1% and NPV 99% according to observer A, and 98.0%, 99.6%, 94.3%, 97.7% and 99%, respectively, according to observer B. Vessel-based accuracy was 99.0%, sensitivity 99.6%, specificity 98.7%, PPV 97.8%, and NPV 99.7% according to observer A, and 98.9%, 99.6%, 98.5%, 97.3%, and 99.7%, respectively, according to observer B. Interobserver reading differences were not significant. The interobserver agreement was good, with a kappa (κ) value of 0.931 for patient-based evaluation, 0.934 for aneurysmbased evaluation and 0.953 for vessel-based evaluation. Conclusions: Our results demonstrate the effectiveness of high-resolution MRA using a single-artery-highlighting technique for accurate diagnosis of intracranial aneurysms in a large cohort of patients with suspected aneurysms. Springer-Verlag, 2012 Magnetic resonance angiography nationallicence Intracranial aneurysm nationallicence Digital subtraction angiography nationallicence Rotational digital subtraction angiography nationallicence Volume rendering nationallicence Risonanza Magnetica nationallicence Aneurisma intracranico nationallicence Angiografia con sottrazione digitale nationallicence Angiografia con sottrazione digitale rotazionale nationallicence Volume rendering nationallicence Li Hui Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut Yan Lei Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut Li Ming-Hua Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut Li Yong-Dong Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut Tan Hua-Qiao Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut Gu Bin-Xian Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut Wang Wu Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut La radiologia medica Springer-Verlag 118/8(2013-12-01), 1379-1387 0033-8362 118:8<1379 2013 118 11547 https://doi.org/10.1007/s11547-012-0871-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0871-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Li Hui Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 700 1- Yan Lei Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 700 1- Li Ming-Hua Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 700 1- Li Yong-Dong Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 700 1- Tan Hua-Qiao Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 700 1- Gu Bin-Xian Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 700 1- Wang Wu Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China aut NATIONALLICENCE 773 0- La radiologia medica Springer-Verlag 118/8(2013-12-01), 1379-1387 0033-8362 118:8<1379 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer