naa a22 4500 51074818X CHVBK 20180411083054.0 cr unu---uuuuu 180411e20130801xx s 000 0 eng 10.1007/s11547-012-0876-9 doi (NATIONALLICENCE)springer-10.1007/s11547-012-0876-9 Dynamic contrast-enhanced MR evaluation of prostate cancer before and after endorectal high-intensity focused ultrasound [Elektronische Daten] [R. Del Vescovo, F. Pisanti, V. Russo, S. Battisti, R. Cazzato, F. D' Agostino, F. Giurazza, C. Quattrocchi, E. Faiella, R. Setola, R. Giulianelli, R. Grasso, B. Beomonte Zobel] La risonanza magnetica perfusionale nella valutazione dell'adenocarcinoma della prostata prima e dopo HIFU transrettale Purpose: The authors sought to determine the diagnostic performance of dynamic contrast-enhanced magnetic resonance (DCE-MR) imaging in the evaluation of prostate cancer before and after transrectal high-intensity focused ultrasound (HIFU) treatment. Materials and methods: We analysed 25 patients with prostate cancer. The prostate-specific antigen (PSA) value was evaluated 1, 4 and 6 months after treatment. DCE-MR imaging was performed the day prior to and 1, 4 and 6 months after HIFU treatment. Transrectal prostate biopsies were obtained at the time of diagnosis and 6 months after treatment. Results: Before treatment, intraglandular lesions were considered to be potential sites of neoplasm and subsequently confirmed as sites of prostate adenocarcinoma in all 25 patients based on prostatespecific antigen (PSA) values and histological examinations (rho=1; p<0.001). Using histology as the gold standard, DCE-MR imaging displayed 100% sensitivity, 100% specificity, 100% positive predictive value and 100% negative predictive value before treatment. After HIFU treatment, DCE-MR imaging showed 100% sensitivity and 96% specificity. Conclusions: DCE-MR imaging can be used to visualise prostate adenocarcinoma. Several morphological and postgadolinium modifications in the follow-up DCE-MR images after HIFU treatment were also observed. Springer-Verlag Italia, 2012 MRI nationallicence Prostate cancer nationallicence HIFU nationallicence D-CE-MR nationallicence DYCHO nationallicence Carcinoma della prostata nationallicence HIFU nationallicence RM-P nationallicence DYCHO nationallicence Del Vescovo R. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Pisanti F. Department of Urology, Villa Tiberia, Rome, Italy aut Russo V. Interdisciplinary Center for Biomedical Research, Campus Bio-Medico, University of Rome, Rome, Italy aut Battisti S. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Cazzato R. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut D' Agostino F. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Giurazza F. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Quattrocchi C. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Faiella E. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Setola R. Interdisciplinary Center for Biomedical Research, Campus Bio-Medico, University of Rome, Rome, Italy aut Giulianelli R. Department of Urology, Villa Tiberia, Rome, Italy aut Grasso R. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut Beomonte Zobel B. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut La radiologia medica Springer Milan 118/5(2013-08-01), 851-862 0033-8362 118:5<851 2013 118 11547 https://doi.org/10.1007/s11547-012-0876-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0876-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Del Vescovo R. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Pisanti F. Department of Urology, Villa Tiberia, Rome, Italy aut NATIONALLICENCE 700 1- Russo V. Interdisciplinary Center for Biomedical Research, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Battisti S. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Cazzato R. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- D' Agostino F. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Giurazza F. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Quattrocchi C. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Faiella E. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Setola R. Interdisciplinary Center for Biomedical Research, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Giulianelli R. Department of Urology, Villa Tiberia, Rome, Italy aut NATIONALLICENCE 700 1- Grasso R. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 700 1- Beomonte Zobel B. Department of Radiology, Campus Bio-Medico, University of Rome, Rome, Italy aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/5(2013-08-01), 851-862 0033-8362 118:5<851 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer