naa a22 4500 510748325 CHVBK 20180411083055.0 cr unu---uuuuu 180411e20130301xx s 000 0 eng 10.1007/s11547-012-0802-4 doi (NATIONALLICENCE)springer-10.1007/s11547-012-0802-4 Embolisation of bone metastases from renal cancer [Elektronische Daten] [G. Rossi, A. Mavrogenis, R. Casadei, G. Bianchi, C. Romagnoli, E. Rimondi, P. Ruggieri] Embolizzazione delle metastasi ossee da carcinoma renale Purpose: This study was done to evaluate embolisation for palliative and/or adjuvant treatment of bone metastases from renal cell carcinoma and discuss the clinical and imaging results. Materials and methods: We retrospectively studied 107 patients with bone metastases from renal cell carcinoma treated from December 2002 to January 2011 with 163 embolisations using N-2-butyl cyanoacrylate (NBCA). Mean tumour diameter before embolisation was 8.8 cm and mean follow-up 4 years. Clinical and imaging effects of treatment were evaluated at follow-up examinations with a pain score scale, analgesic use, hypoattenuating areas, tumour size and ossification. Results: A clinical response was achieved in 157 (96%) and no response in six embolisations of sacroiliac metastases. Mean duration of clinical response was 10 (range 1-12) months. Hypoattenuating areas resembling tumour necrosis were observed in all patients. Variable ossification appeared in 41 patients. Mean maximal tumour diameter after embolisation was 4.0 cm. One patient had intraprocedural tear of the left L3 artery and iliopsoas haemorrhage and was treated with occlusion of the bleeding vessel with NBCA. All patients had variable ischaemic pain that recovered completely within 2-4 days. Postembolisation syndrome was diagnosed after 15 embolisations (9.2%). Transient paraesthesias in the lower extremities were observed after 25 embolisations (25%) of pelvis and sacrum metastatic lesions. Conclusions: Embolisation with NBCA is recommended as primary or palliative treatment of bone metastases from renal cell carcinoma. Strict adherence to the principles of transcatheter embolisation is important to avoid complications. Springer-Verlag Italia, 2012 Selective embolization nationallicence NBCA nationallicence Metastatic bone disease nationallicence Renal cell carcinoma nationallicence Embolizzazione selettiva nationallicence NBCA nationallicence Metastasi ossee nationallicence Carcinoma a cellule renali nationallicence Rossi G. Department of Interventional Angiographic Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy aut Mavrogenis A. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut Casadei R. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut Bianchi G. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut Romagnoli C. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut Rimondi E. Department of Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy aut Ruggieri P. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut La radiologia medica Springer Milan 118/2(2013-03-01), 291-302 0033-8362 118:2<291 2013 118 11547 https://doi.org/10.1007/s11547-012-0802-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11547-012-0802-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rossi G. Department of Interventional Angiographic Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy aut NATIONALLICENCE 700 1- Mavrogenis A. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Casadei R. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Bianchi G. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Romagnoli C. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Rimondi E. Department of Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy aut NATIONALLICENCE 700 1- Ruggieri P. Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy aut NATIONALLICENCE 773 0- La radiologia medica Springer Milan 118/2(2013-03-01), 291-302 0033-8362 118:2<291 2013 118 11547 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer