naa a22 4500 510751121 CHVBK 20180411083105.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s11270-013-1665-3 doi (NATIONALLICENCE)springer-10.1007/s11270-013-1665-3 Distribution and Risk Assessment of Pharmaceutical Compounds in River Sediments from Doñana Park (Spain) [Elektronische Daten] [D. Camacho-Muñoz, J. Martín, J. Santos, I. Aparicio, E. Alonso] The occurrence of 16 pharmaceutical compounds in river sediments from Doñana National Park was investigated, as well as the ecotoxicological risk to the ecosystems of this well-known protected zone. Eight of the 16 pharmaceuticals were present in sediments. The highest concentrations in river sediments concern to diclofenac, salicylic acid and caffeine (52.1, 27.2 and 25.4μg/kgdm). Naproxen, carbamazepine, propranolol, 17β-estradiol and estriol were the other pharmaceutical compounds detected in sediment samples. The relation between the concentration of these pharmaceutical compounds in sediments and river water in contact with was also investigated. While some compounds were detected exclusively in sediment samples (diclofenac, 17β-estradiol and estriol), others were detected only in surface waters in contact with (ibuprofen, ketoprofen and gemfibrozil). The outcome analyses of the ecotoxicological risk assessment showed that the presence of all studied pharmaceutical compounds involved a high toxicological risk at short and long term to Doñana ecosystem. Springer Science+Business Media Dordrecht, 2013 Doñana National Park nationallicence Pharmaceutical compound nationallicence Sediment nationallicence Risk assessment nationallicence Determination nationallicence Camacho-Muñoz D. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut Martín J. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut Santos J. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut Aparicio I. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut Alonso E. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut Water, Air, & Soil Pollution Springer Netherlands 224/10(2013-10-01), 1-15 0049-6979 224:10<1 2013 224 11270 https://doi.org/10.1007/s11270-013-1665-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11270-013-1665-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Camacho-Muñoz D. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut NATIONALLICENCE 700 1- Martín J. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut NATIONALLICENCE 700 1- Santos J. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut NATIONALLICENCE 700 1- Aparicio I. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut NATIONALLICENCE 700 1- Alonso E. Department of Analytical Chemistry, University of Seville, C/Virgen de África 7, 41011, Seville, Spain aut NATIONALLICENCE 773 0- Water, Air, & Soil Pollution Springer Netherlands 224/10(2013-10-01), 1-15 0049-6979 224:10<1 2013 224 11270 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer