naa a22 4500 510751784 CHVBK 20180411083107.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s11270-013-1570-9 doi (NATIONALLICENCE)springer-10.1007/s11270-013-1570-9 Relative Contribution of Endocrine-disrupting Chemicals to the Estrogenic Potency of Marine Sediments of Osaka Bay, Japan [Elektronische Daten] [Jiro Koyama, Asami Kitoh, Makoto Nakai, Kumiko Kohno, Hiroyuki Tanaka, Seiichi Uno] Although concentrations of endocrine-disrupting chemicals (EDCs) in seawaters of Japan are relatively low, vitellogenin and ovotestis inductions are still being observed in some males of mullet and flounder collected in coastal areas. These fish species are benthic and could be affected by EDCs in marine sediments. Therefore, the concentrations of EDCs in marine sediments of Osaka Bay were determined by LC-MS/MS. In addition, the estrogen receptor binding potencies as estrogenic potencies of these sediments were assessed by the medaka estrogen receptor-α binding assay. Results show that estrogenic potencies were higher in sediments of the inner part of the bay especially at station 13 (off Sakai City) where quite strong estrogenic potency was detected. Through calculation of total E2 equivalent concentration (EEQ) in sediments, it was established that approximately 50% of estrogenic potency was due to nonylphenol (NP), estrone and 17β-estradiol, suggesting that these compounds play important roles as endocrine disruptors in coastal environments of Osaka Bay. Springer Science+Business Media Dordrecht, 2013 Estrogen-disrupting chemicals nationallicence E2 equivalent concentration nationallicence Marine sediments nationallicence Osaka Bay nationallicence Koyama Jiro Faculty of Fisheries, Kagoshima University, 4-50-20 Shimoarata, 890-0056, Kagoshima, Japan aut Kitoh Asami Graduate School of Fisheries, Kagoshima University, 4-50-20 Shimoarata, 890-0056, Kagoshima, Japan aut Nakai Makoto Chemical Evaluation and Research Institute, 1600 Shimotakano, Sugito-machi, 345-0043, Saitama, Japan aut Kohno Kumiko Environment Conservation Division, National Research Institute of Fisheries and Environment of Inland Sea, Hiroshima, Japan aut Tanaka Hiroyuki Environment Conservation Division, National Research Institute of Fisheries and Environment of Inland Sea, Hiroshima, Japan aut Uno Seiichi Faculty of Fisheries, Kagoshima University, 4-50-20 Shimoarata, 890-0056, Kagoshima, Japan aut Water, Air, & Soil Pollution Springer Netherlands 224/5(2013-05-01), 1-9 0049-6979 224:5<1 2013 224 11270 https://doi.org/10.1007/s11270-013-1570-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11270-013-1570-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koyama Jiro Faculty of Fisheries, Kagoshima University, 4-50-20 Shimoarata, 890-0056, Kagoshima, Japan aut NATIONALLICENCE 700 1- Kitoh Asami Graduate School of Fisheries, Kagoshima University, 4-50-20 Shimoarata, 890-0056, Kagoshima, Japan aut NATIONALLICENCE 700 1- Nakai Makoto Chemical Evaluation and Research Institute, 1600 Shimotakano, Sugito-machi, 345-0043, Saitama, Japan aut NATIONALLICENCE 700 1- Kohno Kumiko Environment Conservation Division, National Research Institute of Fisheries and Environment of Inland Sea, Hiroshima, Japan aut NATIONALLICENCE 700 1- Tanaka Hiroyuki Environment Conservation Division, National Research Institute of Fisheries and Environment of Inland Sea, Hiroshima, Japan aut NATIONALLICENCE 700 1- Uno Seiichi Faculty of Fisheries, Kagoshima University, 4-50-20 Shimoarata, 890-0056, Kagoshima, Japan aut NATIONALLICENCE 773 0- Water, Air, & Soil Pollution Springer Netherlands 224/5(2013-05-01), 1-9 0049-6979 224:5<1 2013 224 11270 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer