naa a22 4500 510752101 CHVBK 20180411083108.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s11270-013-1575-4 doi (NATIONALLICENCE)springer-10.1007/s11270-013-1575-4 Bioaccumulation, Elimination, and Toxic Effect of Cadmium on Structure of Gills and Hepatopancreas of Freshwater Prawn Macrobrachium sintangese (De Man, 1898) [Elektronische Daten] [Agoes Soegianto, Dwi Winarni, Usreg Handayani, Hartati,] The objectives of this study were to determine the acute toxicity of cadmium and to examine the bioaccumulation and elimination of cadmium in different tissues of the freshwater prawn Macrobrachium sintangese. It also evaluated the structural damage of gills and hepatopancreas of M. sintangese when administered to sublethal cadmium concentration and when exposed prawns were transferred to cadmium-free media. According to the mortality data, the 96h LC50 value of Cd to M. sintangese was 86μg/L. The highest cadmium accumulation was observed in gills, followed by the hepatopancreas, and the abdominal muscle. After being transferred to cadmium-free media, the highest cadmium elimination was observed in abdominal muscle, followed by the gills and hepatopancreas. The gills of prawns exposed to cadmium exhibited a severe hyperplasia, vacuolization, and multiple necroses which resulted to the swelling of lamellae. After transferring the cadmium-exposed prawns into the control media, the histopathological effects decreased. Severe alterations to the hepatopancreatic tissue were observed in prawns exposed to cadmium. The tubular epithelial cells were heavily vacuolated and even ruptured. The number of large vacuoles and R cells appeared in the tubular epithelial cells of the hepatopancreas. After transferring to the control media, the histological alterations of the hepatopancreas decreased. The tubular epithelial cells began to rearrange to the normal structure. The number of R cells and B cells were noted in the epithelial cells. The thickness of tubular epithelial cells was comparable to the controls. Due to the sensitivity of M. sintangese to cadmium, therefore this species potentially can be used as a test organism in toxicity assays. Springer Science+Business Media Dordrecht, 2013 Bioaccumulation nationallicence Elimination nationallicence Cadmium nationallicence Gills nationallicence Hepatopancreas nationallicence Macrobrachium sintangese nationallicence Soegianto Agoes Department of Biology, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut Winarni Dwi Department of Biology, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut Handayani Usreg Department of Chemistry, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut Hartati, Department of Chemistry, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut Water, Air, & Soil Pollution Springer Netherlands 224/5(2013-05-01), 1-10 0049-6979 224:5<1 2013 224 11270 https://doi.org/10.1007/s11270-013-1575-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11270-013-1575-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Soegianto Agoes Department of Biology, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut NATIONALLICENCE 700 1- Winarni Dwi Department of Biology, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut NATIONALLICENCE 700 1- Handayani Usreg Department of Chemistry, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut NATIONALLICENCE 700 1- Hartati Department of Chemistry, Faculty of Sciences and Technology, Airlangga University, Kampus C, Jl. Mulyorejo, 60115, Surabaya, Indonesia aut NATIONALLICENCE 773 0- Water, Air, & Soil Pollution Springer Netherlands 224/5(2013-05-01), 1-10 0049-6979 224:5<1 2013 224 11270 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer