naa a22 4500 510760430 CHVBK 20180411083137.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s11420-013-9346-8 doi (NATIONALLICENCE)springer-10.1007/s11420-013-9346-8 Targeted Preoperative Autologous Blood Donation in Total Knee Arthroplasty Reduces the Need for Postoperative Transfusion [Elektronische Daten] [Jad Bou Monsef, Johannes Buckup, David Mayman, Robert Marx, Amar Ranawat, Friedrich Boettner] Background: Preoperative donation of autologous blood has been widely used to minimize the potential risk of allogeneic transfusions in total knee arthroplasty. A previous study from our center revealed that preoperative autologous donation reduces the allogeneic blood exposure for anemic patients but has no effect for non-anemic patients. Questions/Purposes: The current study investigates the impact of a targeted blood donation protocol on overall transfusion rates and the incidence of allogeneic blood transfusions. Methods: Prospectively, 372 patients undergoing 425 unilateral primary knee replacements were preoperatively screened by the Blood Preservation Center between 2009 and 2012. Anemic patients with a hemoglobin level less than 13.5g/dL were advised to donate blood, while non-anemic patients did not donate. Results: Non-anemic patients who did not donate blood required allogeneic blood transfusions in 5.9% of the patients. The overall rate of allogeneic transfusion was significantly lower for anemic patients who donated autologous blood (group A, 9%) than those who did not donate (group B, 33%; p < 0.001). Donating autologous blood did increase the overall transfusion rate of anemic patients to 0.84 per patient in group A compared to 0.41 per patient in group B (p < 0.001). Conclusion: This investigation confirms that abandoning preoperative autologous blood donation for non-anemic patients does not increase allogeneic blood transfusion rates but significantly lowers overall transfusion rates. Hospital for Special Surgery, 2013 anemia nationallicence total knee arthroplasty nationallicence blood management nationallicence preoperative autologous blood donation nationallicence allogeneic transfusion nationallicence Bou Monsef Jad Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut Buckup Johannes Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut Mayman David Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut Marx Robert Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut Ranawat Amar Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut Boettner Friedrich Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut HSS Journal ® Springer US; http://www.springer-ny.com 9/3(2013-10-01), 214-217 1556-3316 9:3<214 2013 9 11420 https://doi.org/10.1007/s11420-013-9346-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11420-013-9346-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bou Monsef Jad Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut NATIONALLICENCE 700 1- Buckup Johannes Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut NATIONALLICENCE 700 1- Mayman David Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut NATIONALLICENCE 700 1- Marx Robert Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut NATIONALLICENCE 700 1- Ranawat Amar Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut NATIONALLICENCE 700 1- Boettner Friedrich Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA aut NATIONALLICENCE 773 0- HSS Journal ® Springer US; http://www.springer-ny.com 9/3(2013-10-01), 214-217 1556-3316 9:3<214 2013 9 11420 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer