naa a22 4500 510763413 CHVBK 20180411083147.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s12094-013-1019-z doi (NATIONALLICENCE)springer-10.1007/s12094-013-1019-z Research opportunities in intraoperative radiation therapy: the next decade 2013-2023 [Elektronische Daten] [F. Calvo, C. Sole, M. González, E. Tangco, J. López-Tarjuelo, I. Koubychine, J. Santos, J. Pascau, R. Herranz, C. Ferrer] The reality of intraoperative radiation therapy (IORT) practice is consistent with an efficient and highly precise radiation therapy technique to safely boost areas at risk for local recurrence. Long-term clinical experience has shown that IORT-containing multi-modality regimens appear to improve local disease control, if not survival in many diseases. Research with IORT is a multidisciplinary scenario that covers knowledge from radiation beam adapted development to advance molecular biology for bio-predictability of outcome. The technical parameters employed in IORT procedures are important information to be recorded for quality assurance and clinical results analysis. In addition, specific treatment planning systems for IORT procedures are available, to help in the treatment decision-making process. A systematic revision of opportunities for research and innovation in IORT is reported including radiation beam modulation, delivery, dosimetry and planning; infrastructure and treatment factors; experimental and clinical radiobiology; clinical trials, innovation and translational research development. Federación de Sociedades Españolas de Oncología (FESEO), 2013 Intraoperative radiation therapy nationallicence Cancer research nationallicence Treatment planning nationallicence Biomolecular markers nationallicence Calvo F. Department of Oncology, Hospital General Universitario Gregorio Marañon, C/Doctor Esquerdo, 46, 28007, Madrid, Spain aut Sole C. Department of Oncology, Hospital General Universitario Gregorio Marañon, C/Doctor Esquerdo, 46, 28007, Madrid, Spain aut González M. Service of Radiation Oncology, Instituto Oncológico, Viña del Mar, Chile aut Tangco E. Service of Radiation Oncology, The Quezon Medical City, Manila, Philippines aut López-Tarjuelo J. Service of Medical Physics, Hospital Provincial de Castellón, Castellón, Spain aut Koubychine I. Institute of Energetic Techniques, Universidad Politecnica de Cataluña, Barcelona, Spain aut Santos J. School of Medicine, Universidad Complutense, Madrid, Spain aut Pascau J. Department of Experimental Medicine and Surgery, Hospital General Universitario Gregorio Marañon, Madrid, Spain aut Herranz R. Service of Radiation Oncology, Hospital General Universitario Gregorio Marañon, Madrid, Spain aut Ferrer C. Institute of Oncology, Hospital Provincial de Castellón, Castellón, Spain aut Clinical and Translational Oncology Springer Milan 15/9(2013-09-01), 683-690 1699-048X 15:9<683 2013 15 12094 https://doi.org/10.1007/s12094-013-1019-z text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12094-013-1019-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Calvo F. Department of Oncology, Hospital General Universitario Gregorio Marañon, C/Doctor Esquerdo, 46, 28007, Madrid, Spain aut NATIONALLICENCE 700 1- Sole C. Department of Oncology, Hospital General Universitario Gregorio Marañon, C/Doctor Esquerdo, 46, 28007, Madrid, Spain aut NATIONALLICENCE 700 1- González M. Service of Radiation Oncology, Instituto Oncológico, Viña del Mar, Chile aut NATIONALLICENCE 700 1- Tangco E. Service of Radiation Oncology, The Quezon Medical City, Manila, Philippines aut NATIONALLICENCE 700 1- López-Tarjuelo J. Service of Medical Physics, Hospital Provincial de Castellón, Castellón, Spain aut NATIONALLICENCE 700 1- Koubychine I. Institute of Energetic Techniques, Universidad Politecnica de Cataluña, Barcelona, Spain aut NATIONALLICENCE 700 1- Santos J. School of Medicine, Universidad Complutense, Madrid, Spain aut NATIONALLICENCE 700 1- Pascau J. Department of Experimental Medicine and Surgery, Hospital General Universitario Gregorio Marañon, Madrid, Spain aut NATIONALLICENCE 700 1- Herranz R. Service of Radiation Oncology, Hospital General Universitario Gregorio Marañon, Madrid, Spain aut NATIONALLICENCE 700 1- Ferrer C. Institute of Oncology, Hospital Provincial de Castellón, Castellón, Spain aut NATIONALLICENCE 773 0- Clinical and Translational Oncology Springer Milan 15/9(2013-09-01), 683-690 1699-048X 15:9<683 2013 15 12094 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer