naa a22 4500 510763588 CHVBK 20180411083148.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s12094-013-1087-0 doi (NATIONALLICENCE)springer-10.1007/s12094-013-1087-0 SEOM clinical guidelines for the treatment of osteosarcoma in adults-2013 [Elektronische Daten] [A. Redondo, J. Cruz, A. Lopez-Pousa, F. Barón] The diagnosis and treatment of osteosarcoma should be performed by an experienced multidisciplinary team. Considering it is a systemic disease, chemotherapy is essential for long-term success. The drugs most commonly used are: cisplatin, adriamycin, high-dose methotrexate, ifosfamide, etoposide, and, more recently, mifamurtide. The neoadjuvant chemotherapy allows to know tumour chemosensitivity and getting the main prognostic factor: the percentage of tumour necrosis. In addition to chemotherapy, it is important to conduct surgical resection of primary tumour with wide margins, and in disseminated disease also to attempt resection of pulmonary metastasis. Federación de Sociedades Españolas de Oncología (FESEO), 2013 Osteosarcoma nationallicence Diagnosis nationallicence Chemotherapy nationallicence Surgery nationallicence Mifamurtide nationallicence Multidisciplinary team nationallicence Redondo A. Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid Pº de la Castellana, 261, 28046, Madrid, Spain aut Cruz J. University Hospital of the Canaries, Tenerife, Spain aut Lopez-Pousa A. Sant Pau Hospital, Barcelona, Spain aut Barón F. Santiago University, Hospital Complex, Santiago de Compostela, Spain aut Clinical and Translational Oncology Springer Milan 15/12(2013-12-01), 1037-1043 1699-048X 15:12<1037 2013 15 12094 https://doi.org/10.1007/s12094-013-1087-0 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12094-013-1087-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Redondo A. Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid Pº de la Castellana, 261, 28046, Madrid, Spain aut NATIONALLICENCE 700 1- Cruz J. University Hospital of the Canaries, Tenerife, Spain aut NATIONALLICENCE 700 1- Lopez-Pousa A. Sant Pau Hospital, Barcelona, Spain aut NATIONALLICENCE 700 1- Barón F. Santiago University, Hospital Complex, Santiago de Compostela, Spain aut NATIONALLICENCE 773 0- Clinical and Translational Oncology Springer Milan 15/12(2013-12-01), 1037-1043 1699-048X 15:12<1037 2013 15 12094 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer