naa a22 4500 510763626 CHVBK 20180411083148.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s12094-013-1082-5 doi (NATIONALLICENCE)springer-10.1007/s12094-013-1082-5 SEOM Clinical guidelines for the treatment of advanced colorectal cancer 2013 [Elektronische Daten] [E. Casado-Saenz, J. Feliu, M. Gomez-España, A. Sanchez-Gastaldo, R. Garcia-Carbonero] Colorectal cancer (CRC) is the most common malignant tumor in Western countries. Despite efforts made to implement screening programmes for early detection and treatment, still half of the patients present or will eventually develop distant metastasis. Management of advanced CRC should be discussed within an experienced multidisciplinary team, to adequately select the most appropriate systemic therapeutic option, as well as the optimal way to integrate it with surgical procedures when indicated. Disease localization and extent, resectability of primary and metastatic disease, tumor biology and dynamics, clinical symptoms, personal preferences and patient's ability to tolerate intensive chemotherapy or extensive surgical procedures are the key factors to properly design a customized treatment plan. The aim of the current manuscript is to provide synthetic practical guidelines regarding therapeutic options for advanced CRC. Federación de Sociedades Españolas de Oncología (FESEO), 2013 Colorectal cancer nationallicence Guidelines nationallicence Chemotherapy nationallicence Surgery nationallicence Casado-Saenz E. Medical Oncology Department, Hospital Infanta Sofia, Madrid, Spain aut Feliu J. Medical Oncology Department, Hospital La Paz, Madrid, Spain aut Gomez-España M. Medical Oncology Department, Hospital Reina Sofia, Córdoba, Spain aut Sanchez-Gastaldo A. Servicio de Oncología Médica, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS) [Universidad de Sevilla, CSIC, HUVR], Avenida Manuel Siurot, S/N, 41013, Sevilla, Spain aut Garcia-Carbonero R. Servicio de Oncología Médica, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS) [Universidad de Sevilla, CSIC, HUVR], Avenida Manuel Siurot, S/N, 41013, Sevilla, Spain aut Clinical and Translational Oncology Springer Milan 15/12(2013-12-01), 996-1003 1699-048X 15:12<996 2013 15 12094 https://doi.org/10.1007/s12094-013-1082-5 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12094-013-1082-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Casado-Saenz E. Medical Oncology Department, Hospital Infanta Sofia, Madrid, Spain aut NATIONALLICENCE 700 1- Feliu J. Medical Oncology Department, Hospital La Paz, Madrid, Spain aut NATIONALLICENCE 700 1- Gomez-España M. Medical Oncology Department, Hospital Reina Sofia, Córdoba, Spain aut NATIONALLICENCE 700 1- Sanchez-Gastaldo A. Servicio de Oncología Médica, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS) [Universidad de Sevilla, CSIC, HUVR], Avenida Manuel Siurot, S/N, 41013, Sevilla, Spain aut NATIONALLICENCE 700 1- Garcia-Carbonero R. Servicio de Oncología Médica, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS) [Universidad de Sevilla, CSIC, HUVR], Avenida Manuel Siurot, S/N, 41013, Sevilla, Spain aut NATIONALLICENCE 773 0- Clinical and Translational Oncology Springer Milan 15/12(2013-12-01), 996-1003 1699-048X 15:12<996 2013 15 12094 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer