naa a22 4500 510763944 CHVBK 20180411083149.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s12094-013-1023-3 doi (NATIONALLICENCE)springer-10.1007/s12094-013-1023-3 Intimal-medial thickness and carotid arteries lumen in irradiated patients for head and neck cancer: preliminary data of an observational study [Elektronische Daten] [M. Faruolo, A. Fiorentino, G. Gallucci, L. Lapadula, V. Fusco] Objectives: To investigate the effect of external beam radiotherapy (EBRT) for head and neck cancer (HNC) the intimal-medial thickness (IMT) and the lumen of the carotid artery. Methods: Patients with HNC and an indication for EBRT were enrolled. A carotid artery color Doppler examination was performed before and 6 and 12months after EBRT. Results: From 2008 to 2011, 50 patients were enrolled. The mean carotid IMT was 0.9 vs. 1.02mm before and 6months after EBRT, respectively (p=0.0001). The common carotid artery lumen was narrowed without statistical significance, 6months after EBRT (p=0.3). 1year from EBRT, the IMT increase and the lumen reduction were statistically significant (p=0.001, p=0.01, respectively). Neurological events (stroke or TIA) were not observed. Conclusions: Our data showed a significant IMT increase 6months from EBRT without a corresponding narrowing of the common carotid lumen while a significant increase 12months after EBRT. Federación de Sociedades Españolas de Oncología (FESEO), 2013 Carotid artery nationallicence Radiation nationallicence Ultrasonography nationallicence Head and neck cancer nationallicence Faruolo M. Cardiology Service, IRCCS/CROB, Rionero in Vulture (PZ), Italy aut Fiorentino A. Department of Radiation Oncology, IRCCS/CROB, San Pio 1 Street, 85028, Rionero in Vulture (PZ), Italy aut Gallucci G. Cardiology Service, IRCCS/CROB, Rionero in Vulture (PZ), Italy aut Lapadula L. Department of Radiation Oncology, IRCCS/CROB, San Pio 1 Street, 85028, Rionero in Vulture (PZ), Italy aut Fusco V. Department of Radiation Oncology, IRCCS/CROB, San Pio 1 Street, 85028, Rionero in Vulture (PZ), Italy aut Clinical and Translational Oncology Springer Milan 15/10(2013-10-01), 861-864 1699-048X 15:10<861 2013 15 12094 https://doi.org/10.1007/s12094-013-1023-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12094-013-1023-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Faruolo M. Cardiology Service, IRCCS/CROB, Rionero in Vulture (PZ), Italy aut NATIONALLICENCE 700 1- Fiorentino A. Department of Radiation Oncology, IRCCS/CROB, San Pio 1 Street, 85028, Rionero in Vulture (PZ), Italy aut NATIONALLICENCE 700 1- Gallucci G. Cardiology Service, IRCCS/CROB, Rionero in Vulture (PZ), Italy aut NATIONALLICENCE 700 1- Lapadula L. Department of Radiation Oncology, IRCCS/CROB, San Pio 1 Street, 85028, Rionero in Vulture (PZ), Italy aut NATIONALLICENCE 700 1- Fusco V. Department of Radiation Oncology, IRCCS/CROB, San Pio 1 Street, 85028, Rionero in Vulture (PZ), Italy aut NATIONALLICENCE 773 0- Clinical and Translational Oncology Springer Milan 15/10(2013-10-01), 861-864 1699-048X 15:10<861 2013 15 12094 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer