naa a22 4500 510764223 CHVBK 20180411083150.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s12094-012-0946-4 doi (NATIONALLICENCE)springer-10.1007/s12094-012-0946-4 Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: parotid glands [Elektronische Daten] [A. Fiorentino, M. Cozzolino, R. Caivano, P. Pedicini, C. Chiumento, C. Oliviero, S. Clemente, V. Fusco] Purpose: To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods: Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). The PG mean dose (D mean), the dose to 50% of the volume, and the percent of volume receiving 30 and 50Gy were measured by the dose volume histogram. Results: 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCTplan I. The D mean increased significantly only for ipsilateral PG (p=0.02) at week 3. Conclusion: During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the time-check-point. Federación de Sociedades Españolas de Oncología (FESEO), 2012 Head and neck cancer nationallicence IMRT nationallicence Organ at risk nationallicence Parotid glands nationallicence Radiotherapy nationallicence Fiorentino A. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Cozzolino M. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Caivano R. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Pedicini P. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Chiumento C. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Oliviero C. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Clemente S. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Fusco V. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut Clinical and Translational Oncology Springer Milan 15/5(2013-05-01), 412-415 1699-048X 15:5<412 2013 15 12094 https://doi.org/10.1007/s12094-012-0946-4 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12094-012-0946-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fiorentino A. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Cozzolino M. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Caivano R. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Pedicini P. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Chiumento C. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Oliviero C. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Clemente S. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 700 1- Fusco V. Radiotherapy Oncology Department, IRCCS-CROB, Rionero in Vulture, Potenza, Italy aut NATIONALLICENCE 773 0- Clinical and Translational Oncology Springer Milan 15/5(2013-05-01), 412-415 1699-048X 15:5<412 2013 15 12094 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer