naa a22 4500 510764231 CHVBK 20180411083150.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s12094-012-0933-9 doi (NATIONALLICENCE)springer-10.1007/s12094-012-0933-9 Clinical report on transarterial neoadjuvant chemotherapy of malignant fibrous histiocytoma in soft tissue [Elektronische Daten] [Jun Guo, Qiu Cui, Cheng Liu, Jiahong Sui, Ning Jiang, Ju Zhou, Dingfeng Li, Yanjun Zeng] Purpose: To review the experience in transarterial neoadjuvant chemotherapy of malignant fibrous histiocytoma (MFH) in soft tissue and to analyze the factors related to prognosis of MFH in soft tissue. Methods: Between September 1999 and December 2011, 101 cases of MFH in soft tissue patients treated by transarterial administration of Cisplatin, Adriamycin and Norcantharidin were divided into primary group and recurrent group, and the clinical documents were reviewed. Nine factors that might affect prognosis such as age, sex, tumor size, tumor site, tumor infiltration depth, recurrence if any, pathological type, histologic grade and histologic response of chemotherapy were analyzed statistically. Results: The 5-year relapse-free survival rate and the overall survival rate were 70.5 and 75.0%, respectively, in the primary group; 56.1 and 57.9%, respectively, in the recurrent group. Univariate analysis (log-rank test) showed that the factors affecting the prognosis were age (P=0.03), tumor size (P=0.01), pelvic tumor (P=0.02), recurrence if any (P=0.004), histologic grade (P=0.01), and histologic response to chemotherapy (P=0.007). Multivariate analysis showed that the major factors affecting prognosis were pelvic tumor (P=0.01), tumor size (P=0.002), histologic grade (P=0.002), recurrence if any (P=0.0004), and histologic response to chemotherapy (P=0.008). Conclusion: Transarterial neoadjuvant chemotherapy can significantly increase the curative efficacy of chemotherapy and survival rate in MFH treatment. Federación de Sociedades Españolas de Oncología (FESEO), 2012 Malignant fibrous histiocytoma nationallicence Soft tissue nationallicence Transarterial neoadjuvant chemotherapy nationallicence Prognosis nationallicence Guo Jun Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Cui Qiu Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Liu Cheng Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Sui Jiahong Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Jiang Ning Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Zhou Ju Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Li Dingfeng Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut Zeng Yanjun Biomedical Engineering Center, Beijing University of Technology, 100022, Beijing, China aut Clinical and Translational Oncology Springer Milan 15/5(2013-05-01), 370-375 1699-048X 15:5<370 2013 15 12094 https://doi.org/10.1007/s12094-012-0933-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12094-012-0933-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Guo Jun Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Cui Qiu Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Liu Cheng Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Sui Jiahong Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Jiang Ning Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Zhou Ju Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Li Dingfeng Department of Orthopedics, 307 Hospital of PLA, No. 8 East Street, Fengtai District, 100071, Beijing, China aut NATIONALLICENCE 700 1- Zeng Yanjun Biomedical Engineering Center, Beijing University of Technology, 100022, Beijing, China aut NATIONALLICENCE 773 0- Clinical and Translational Oncology Springer Milan 15/5(2013-05-01), 370-375 1699-048X 15:5<370 2013 15 12094 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer