naa a22 4500 510769578 CHVBK 20180411083208.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s11818-013-0606-0 doi (NATIONALLICENCE)springer-10.1007/s11818-013-0606-0 Sweet taste perception not altered after acute sleep deprivation in healthy young men [Elektronische Daten] [P.S. Hogenkamp, E. Nilsson, C.D. Chapman, J. Cedernaes, H. Vogel, S.L. Dickson, J-E Broman, H.B. Schiöth, C. Benedict] Keine veränderte Wahrnehmung des Süßgeschmacks bei gesunden jungen Männern durch akuten Schlafmangel Background: We hypothesized that acutely sleep-deprived participants would rate ascending concentrations of sucrose as more intense and pleasant, than they would do after one night of normal sleep. Such a finding would offer a potential mechanism through which acute sleep loss could promote overeating in humans. Method: A total of 16healthy normal-weight men participated in 2conditions: sleep (permitted between 22:30 and 06:30h) and total sleep deprivation (TSD) respectively. On the morning after regular sleep and TSD, circulating concentrations of ghrelin and glucose were measured. In addition, participants hunger level was assessed by means of visual analogue scales, both before and after a caloric preload. Finally, following the preload, participants rated both intensity and pleasantness of six orally presented yogurt probes with varying sucrose concentrations (2-29 %). Results: Feelings of hunger were significantly more intense under both fasted and sated conditions when subjects were sleep-deprived. In contrast, the change in hunger induced by the preload was similar between the sleep and TSD conditions. Plasma concentrations of ghrelin were significantly higher under conditions of TSD, whereas plasma glucose did not differ between the conditions. No effects were found either on sweet taste intensity or on pleasantness after TSD. Conclusion: One night of TSD increases morning plasma concentrations of the hunger-promoting hormone ghrelin in healthy young men. In contrast, sweet taste perception was not affected by nocturnal wakefulness. This suggests that an altered sweet taste perception is an unlikely mechanism by which TSD enhances food intake. ©The Authors (2013) This article is published with open access at Springerlink.com, 2013 Sleep loss nationallicence Satiety nationallicence Food intake nationallicence Preload nationallicence Ghrelin nationallicence Schlafmangel nationallicence Sättigung nationallicence Nahrungsaufnahme nationallicence Vorspannung nationallicence Ghrelin nationallicence Hogenkamp P.S. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Nilsson E. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Chapman C.D. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Cedernaes J. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Vogel H. Department of Physiology/Endocrinology, The Sahlgrenska Academy at the University of Gothenburg, 405 30, Gothenburg, Sweden aut Dickson S.L. Department of Physiology/Endocrinology, The Sahlgrenska Academy at the University of Gothenburg, 405 30, Gothenburg, Sweden aut Broman J-E Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Schiöth H.B. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Benedict C. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut Somnologie - Schlafforschung und Schlafmedizin Springer-Verlag 17/2(2013-06-01), 111-114 1432-9123 17:2<111 2013 17 11818 https://doi.org/10.1007/s11818-013-0606-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11818-013-0606-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hogenkamp P.S. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 700 1- Nilsson E. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 700 1- Chapman C.D. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 700 1- Cedernaes J. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 700 1- Vogel H. Department of Physiology/Endocrinology, The Sahlgrenska Academy at the University of Gothenburg, 405 30, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Dickson S.L. Department of Physiology/Endocrinology, The Sahlgrenska Academy at the University of Gothenburg, 405 30, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Broman J-E Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 700 1- Schiöth H.B. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 700 1- Benedict C. Department of Neuroscience, Uppsala University, 751 24, Uppsala, Sweden aut NATIONALLICENCE 773 0- Somnologie - Schlafforschung und Schlafmedizin Springer-Verlag 17/2(2013-06-01), 111-114 1432-9123 17:2<111 2013 17 11818 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer