naa a22 4500 510773656 CHVBK 20180411083223.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s12022-013-9238-y doi (NATIONALLICENCE)springer-10.1007/s12022-013-9238-y Is There a Role for On-Site Evaluation of Thyroid Fine Needle Aspiration to Reduce the Nondiagnostic Rate? [Elektronische Daten] [Gulcin Simsek, Derun Ertuğrul, Servet Guresci, Hülya Şimşek] The use of immediate on-site evaluation of fine-needle aspiration biopsy (FNAB) specimens can determine the adequacy of specimens and provides a specific preliminary diagnosis. In this prospective study, we evaluated the impact of on-site assessment of thyroid FNAB performed under ultrasound guidance. Totally, 204 (170 female, 34 male) patients (102 on site, 102 control group) were included. The patients were randomized on site and regular cytologic examination groups. Quick May-Grünwald Giemsa stain was used for on-site examination and FNA was continued until adequate aspirate for optimal cytological examination. Two (2.0%) of the 102 patients evaluated with on-site examination had a nondiagnostic result. However, 16 (15.7%) of the 102 patients examined by regular cytologic examination method, had nondiagnostic result. The difference between these two groups was statistically significant (p < 0.0001). The major cause of a nondiagnostic thyroid FNAB specimen is the failure to aspirate a sufficient number of cells necessary for diagnosis cystic lesions. Immediate on-site evaluation can significantly decrease the nondiagnostic rate of thyroid FNAB specimens. Springer Science+Business Media New York, 2013 Onsite nationallicence Thyroid nationallicence Fine needle aspiration nationallicence Simsek Gulcin Department of Pathology, Kecioren Training and Research Hospital, C Atuf Kansu Street 166-4, Çankaya Ankara, Turkey aut Ertuğrul Derun Department of Endocrinology, Kecioren Training and Research Hospital, Ankara, Turkey aut Guresci Servet Department of Pathology, Kecioren Training and Research Hospital, Sanatoryum Street, Ankara, Kecioren, Turkey aut Şimşek Hülya Department of Pathology, Kecioren Training and Research Hospital, Sanatoryum Street, Ankara, Kecioren, Turkey aut Endocrine Pathology Springer US; http://www.springer-ny.com 24/2(2013-06-01), 57-61 1046-3976 24:2<57 2013 24 12022 https://doi.org/10.1007/s12022-013-9238-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12022-013-9238-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Simsek Gulcin Department of Pathology, Kecioren Training and Research Hospital, C Atuf Kansu Street 166-4, Çankaya Ankara, Turkey aut NATIONALLICENCE 700 1- Ertuğrul Derun Department of Endocrinology, Kecioren Training and Research Hospital, Ankara, Turkey aut NATIONALLICENCE 700 1- Guresci Servet Department of Pathology, Kecioren Training and Research Hospital, Sanatoryum Street, Ankara, Kecioren, Turkey aut NATIONALLICENCE 700 1- Şimşek Hülya Department of Pathology, Kecioren Training and Research Hospital, Sanatoryum Street, Ankara, Kecioren, Turkey aut NATIONALLICENCE 773 0- Endocrine Pathology Springer US; http://www.springer-ny.com 24/2(2013-06-01), 57-61 1046-3976 24:2<57 2013 24 12022 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer