naa a22 4500 510776256 CHVBK 20180411083231.0 cr unu---uuuuu 180411e20130401xx s 000 0 eng 10.1007/s12975-013-0255-4 doi (NATIONALLICENCE)springer-10.1007/s12975-013-0255-4 Sudden Unexpected Postnatal Collapse of Newborn Infants: A Review of Cases, Definitions, Risks, and Preventive Measures [Elektronische Daten] [Eric Herlenius, Pierre Kuhn] This study aimed to review available published reports concerning sudden unexpected postnatal collapse (SUPC) of apparently healthy infants within the first days of postnatal life, establish a structured presentation and delineate recommendations for preventive measures. All published reports of SUPC cases were retrospectively analyzed, and three not previously published SUPC cases at Karolinska University Hospital were detailed to exemplify the varying presentations and outcomes of SUPC. We found 398 published cases of SUPC occurring during first postnatal week. Estimated incidence of the SUPC of a presumably healthy infant after birth differs widely, ranging from 2.6 cases to 133 cases/100,000. However, definition, inclusion, and exclusion criteria vary substantially between reports. Our summary indicates that reported SUPC occurs more frequently than expected from recent surveys. About half of the infants die, and of the remaining survivors, half have neurological sequela. Of the 233 cases of sudden unexpected death described, no etiology was found in 153 cases. When a defined time for the SUPC event is described, approximately one third of reported events occur during the first 2h, between 2 and 24h and between 1 and 7days after birth, respectively. Adequate education of caregivers and appropriate surveillance during the first days of newborns should enable us to save hundreds of lives. The Author(s), 2013 Sudden unexpected postnatal collapse nationallicence Prone nationallicence Hypoxia nationallicence Birth asphyxia nationallicence Adenosine nationallicence Prostaglandin nationallicence Cardiorespiratory control nationallicence SUPC : Sudden unexpected postnatal collapse nationallicence eSIDS : Early sudden infant death syndrome nationallicence ALTE : Apparent life threatening event nationallicence SUDI : Sudden unexpected death in infancy nationallicence SUEND : Sudden unexpected early neonatal death nationallicence BE : Base excess nationallicence EEG : Electroencephalography nationallicence CPAP : Continuous positive airway pressure nationallicence HIE : Hypoxic ischemic encephalopathy nationallicence TTN : Transient tachypnea of the newborn nationallicence PFO : Patent foramen ovale nationallicence ICD : International Classification of Disease nationallicence PDA : Patent ductus arteriosus nationallicence PGE2 : Prostaglandin E2 nationallicence mPGES-1 : Microsomal prostaglandin E synthase-1 nationallicence SSC : Safe early skin-to-skin care nationallicence Herlenius Eric Neonatal Unit Q2:07, Department of Women's and Children's Health, Astrid Lindgren Children's Hospital, Karolinska Institutet, 17176, Stockholm, Sweden aut Kuhn Pierre Neonatal Unit Q2:07, Department of Women's and Children's Health, Astrid Lindgren Children's Hospital, Karolinska Institutet, 17176, Stockholm, Sweden aut Translational Stroke Research Springer-Verlag 4/2(2013-04-01), 236-247 1868-4483 4:2<236 2013 4 12975 https://doi.org/10.1007/s12975-013-0255-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12975-013-0255-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Herlenius Eric Neonatal Unit Q2:07, Department of Women's and Children's Health, Astrid Lindgren Children's Hospital, Karolinska Institutet, 17176, Stockholm, Sweden aut NATIONALLICENCE 700 1- Kuhn Pierre Neonatal Unit Q2:07, Department of Women's and Children's Health, Astrid Lindgren Children's Hospital, Karolinska Institutet, 17176, Stockholm, Sweden aut NATIONALLICENCE 773 0- Translational Stroke Research Springer-Verlag 4/2(2013-04-01), 236-247 1868-4483 4:2<236 2013 4 12975 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer