naa a22 4500 510779271 CHVBK 20180411083241.0 cr unu---uuuuu 180411e20130201xx s 000 0 eng 10.1007/s11892-012-0342-z doi (NATIONALLICENCE)springer-10.1007/s11892-012-0342-z Adult Hyperglycemic Crisis: A Review and Perspective [Elektronische Daten] [Devin Steenkamp, Sara Alexanian, Marie McDonnell] Hyperglycemic crisis, which includes Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State, is a common diagnosis in high acuity hospital units and admission rates continue to increase despite preventive strategies. While diabetic ketoacidosis remains a common cause of death in children and adolescents with type 1 diabetes, in adults reported mortality is variable and depends on the severity of metabolic derangement and the presence of other acute and chronic conditions. Hyperosmolar hyperglycemic state, and the overlap syndrome of hyperosmolar ketoacidosis, have a higher overall mortality though outcomes are improving. We discuss the diagnosis, epidemiology, and management strategies with particular reference to commonly encountered pitfalls in care and provide an updated perspective on the shifts in the epidemiology and novel management strategies for these important disorders. Springer Science+Business Media New York, 2012 Hyperglycemic crisis nationallicence Diabetic ketoacidosis nationallicence Hyperglycemic hyperosmolar state nationallicence Adults nationallicence Steenkamp Devin Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston Medical Center, Evans 201, 88 East Newton St., 02118, Boston, MA, USA aut Alexanian Sara Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston Medical Center, Evans 201, 88 East Newton St., 02118, Boston, MA, USA aut McDonnell Marie Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston Medical Center, Evans 201, 88 East Newton St., 02118, Boston, MA, USA aut Current Diabetes Reports Current Science Inc. 13/1(2013-02-01), 130-137 1534-4827 13:1<130 2013 13 11892 https://doi.org/10.1007/s11892-012-0342-z text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11892-012-0342-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Steenkamp Devin Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston Medical Center, Evans 201, 88 East Newton St., 02118, Boston, MA, USA aut NATIONALLICENCE 700 1- Alexanian Sara Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston Medical Center, Evans 201, 88 East Newton St., 02118, Boston, MA, USA aut NATIONALLICENCE 700 1- McDonnell Marie Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston Medical Center, Evans 201, 88 East Newton St., 02118, Boston, MA, USA aut NATIONALLICENCE 773 0- Current Diabetes Reports Current Science Inc 13/1(2013-02-01), 130-137 1534-4827 13:1<130 2013 13 11892 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer