naa a22 4500 51077928X CHVBK 20180411083241.0 cr unu---uuuuu 180411e20130201xx s 000 0 eng 10.1007/s11892-012-0334-z doi (NATIONALLICENCE)springer-10.1007/s11892-012-0334-z Current Treatment Options for Type 2 Diabetes Mellitus in Youth: Today's Realities and Lessons from the TODAY Study [Elektronische Daten] [Minu George, Kenneth Copeland] The incidence of type 2 diabetes in children and adolescents has increased over the last 2 decades, paralleled by an increase in obesity over the same time period. Although the value of lifestyle modification in obese youth is unquestioned, scant evidence for optimal treatment of type 2 diabetes in this age group exists. Despite recent therapeutic drug trials, metformin and insulin are the only medicines currently approved by the U.S. Food and Drug Administration for the treatment of type 2 diabetes in youth. Because of recently amended pharmaceutical regulations, however, it is likely that more antidiabetic medications soon will be added to the armamentarium of therapeutic options for youth with type 2 diabetes. Additionally, the recently published TODAY study comparing safety and efficacy of three treatment regimens in maintaining glycemic control in youth with type 2 diabetes has shed new light on the problem. Springer Science+Business Media New York, 2012 Type 2 diabetes nationallicence Diabetes treatment in youth nationallicence Hyperglycemia nationallicence Insulin resistance nationallicence Insulin sensitivity nationallicence Metformin nationallicence Bariatric surgery nationallicence Diabetes medications nationallicence TODAY trial nationallicence George Minu Department of Pediatrics, Section of Diabetes & Endocrinology, The University of Oklahoma College of Medicine, 1200 Children's Ave, 73104, Oklahoma City, OK, USA aut Copeland Kenneth Department of Pediatrics, Section of Diabetes & Endocrinology, The University of Oklahoma College of Medicine, 1200 Children's Ave, 73104, Oklahoma City, OK, USA aut Current Diabetes Reports Current Science Inc. 13/1(2013-02-01), 72-80 1534-4827 13:1<72 2013 13 11892 https://doi.org/10.1007/s11892-012-0334-z text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11892-012-0334-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- George Minu Department of Pediatrics, Section of Diabetes & Endocrinology, The University of Oklahoma College of Medicine, 1200 Children's Ave, 73104, Oklahoma City, OK, USA aut NATIONALLICENCE 700 1- Copeland Kenneth Department of Pediatrics, Section of Diabetes & Endocrinology, The University of Oklahoma College of Medicine, 1200 Children's Ave, 73104, Oklahoma City, OK, USA aut NATIONALLICENCE 773 0- Current Diabetes Reports Current Science Inc 13/1(2013-02-01), 72-80 1534-4827 13:1<72 2013 13 11892 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer