naa a22 4500 510779506 CHVBK 20180411083242.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s11892-013-0379-7 doi (NATIONALLICENCE)springer-10.1007/s11892-013-0379-7 Vascular Calcification in Diabetes: Mechanisms and Implications [Elektronische Daten] [Janet Snell-Bergeon, Matthew Budoff, John Hokanson] Cardiovascular disease (CVD) remains the leading cause of death among adults with diabetes, and CVD prevention remains a major challenge. Coronary artery calcium (CAC) score measured by electron beam tomography (EBT) or multi-slice detector computed tomography correlates closely with plaque burden and coronary angiography, and predicts coronary events independently of other risk factors. Further, progression of CAC over several years has been shown to predict increased mortality. Coronary calcification is an active process strongly associated with atherosclerotic plaque evolution and is an accepted surrogate endpoint in studies of patients with diabetes older than 30. In this review, recent findings regarding the mechanisms and implications of vascular calcification in diabetes will be discussed. Springer Science+Business Media New York, 2013 Diabetes mellitus nationallicence Type 1 diabetes nationallicence Type 2 diabetes nationallicence Epidemiology nationallicence Cardiovascular disease nationallicence Coronary artery disease nationallicence Atherosclerosis nationallicence Coronary heart disease nationallicence Vascular calcification nationallicence Snell-Bergeon Janet Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, 1775 Aurora Ct, Mail Stop A140, 80045, Aurora, CO, USA aut Budoff Matthew Los Angeles Biomedical Research Institute, 1124 W Carson Street, 90502, Torrance, CA, USA aut Hokanson John Colorado School of Public Health, University of Colorado Anschutz Medical Campus, 80045, Aurora, CO, USA aut Current Diabetes Reports Current Science Inc. 13/3(2013-06-01), 391-402 1534-4827 13:3<391 2013 13 11892 https://doi.org/10.1007/s11892-013-0379-7 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11892-013-0379-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Snell-Bergeon Janet Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, 1775 Aurora Ct, Mail Stop A140, 80045, Aurora, CO, USA aut NATIONALLICENCE 700 1- Budoff Matthew Los Angeles Biomedical Research Institute, 1124 W Carson Street, 90502, Torrance, CA, USA aut NATIONALLICENCE 700 1- Hokanson John Colorado School of Public Health, University of Colorado Anschutz Medical Campus, 80045, Aurora, CO, USA aut NATIONALLICENCE 773 0- Current Diabetes Reports Current Science Inc 13/3(2013-06-01), 391-402 1534-4827 13:3<391 2013 13 11892 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer