naa a22 4500 510780520 CHVBK 20180411083245.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s11692-013-9236-5 doi (NATIONALLICENCE)springer-10.1007/s11692-013-9236-5 Turke Paul Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA aut Making Young from Old: How is Sex Designed to Help? [Elektronische Daten] [Paul Turke] Gametogenesis and syngamy are shown to incorporate, as key elements in their design, structures and processes that help to prevent age-related deterioration that accumulates in adult somas from being transferred directly to newly formed offspring. As such, in addition to producing new gene combinations, sex increases the separation of germ and soma. It follows as a central prediction that offspring of a species that has recently abandoned sex will manifest early in life some of the dysfunctions that formerly manifested only much later in life. These dysfunctions, which can include early onset of age-linked diseases such as cancer, should impede transitioning to non-sex, and therefore would help to account for sex's maintenance. Evidence is reviewed, and found generally to support the hypothesis. Springer Science+Business Media New York, 2013 Antagonistic pleiotropy nationallicence Complexity nationallicence Germ-soma separation nationallicence Maintenance of sex nationallicence Rejuvenation nationallicence Senescence nationallicence Evolutionary Biology Springer US; http://www.springer-ny.com 40/4(2013-12-01), 471-479 0071-3260 40:4<471 2013 40 11692 https://doi.org/10.1007/s11692-013-9236-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11692-013-9236-5 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Turke Paul Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA aut NATIONALLICENCE 773 0- Evolutionary Biology Springer US; http://www.springer-ny.com 40/4(2013-12-01), 471-479 0071-3260 40:4<471 2013 40 11692 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer