naa a22 4500 510786138 CHVBK 20180411083302.0 cr unu---uuuuu 180411e20130301xx s 000 0 eng 10.1007/s12603-012-0434-0 doi (NATIONALLICENCE)springer-10.1007/s12603-012-0434-0 Mortality as an adverse outcome of sarcopenia [Elektronische Daten] [V. Arango-Lopera, P. Arroyo, Luis Gutiérrez-Robledo, M. Perez-Zepeda, M. Cesari] Sarcopenia has an important impact in elderly. Recently the European Working Group on Sarcopenia in Older People (EWGSOP) defined sarcopenia as the loss of muscle mass plus low muscle strength or low physical performance. Lack of clinical sounding outcomes (ie external validity), is one of the flaws of this algorithm. The aim of our study was to determine the association of sarcopenia and mortality in a group of Mexican elderly. A total of 345 elderly were recruited in Mexico City, and followed up for three years. The EWGSOP algorithm was integrated by: gait speed, grip strength and calf circumference. Other covariates were assessed in order to test the independent association of sarcopenia with mortality. Of the 345 subjects, 53.3% were women; with a mean age of 78.5 (SD 7) years. During the three year follow-up a total of 43 (12.4%) subjects died. Age, cognition, ADL, IADL, health self-perception, ischemic heart disease and sarcopenia were associated in the bivariate analysis with survival. Negative predictive value for sarcopenia regarding mortality was of 90%. Kaplan-Meier curves along with their respective log-rank test were significant for sarcopenia. The components of the final Cox-regression multivariate model were age, ischemic heart disease, ADL and sarcopenia. Adjusted HR for age was 3.24 (CI 95% 1.55-6.78 p 0.002), IHD 5.07 (CI 95% 1.89-13.59 p 0.001), health self-perception 5.07 (CI 95% 1.9-13.6 p 0.001), ADL 0.75 (CI 95% 0.56-0.99 p 0.048) and sarcopenia 2.39 (CI 95% 1.05-5.43 p 0.037). Serdi and Springer-Verlag France, 2012 Sarcopenia nationallicence survival nationallicence nutrition in elderly nationallicence Arango-Lopera V. Education Department at Instituto de Geriatría, México D.F, México aut Arroyo P. Research Department at Instituto de Geriatría, México D.F, México aut Gutiérrez-Robledo Luis Instituto de Geriatría, México D.F, México aut Perez-Zepeda M. Research Department at Instituto de Geriatría, México D.F, México aut Cesari M. Gerontopole; Toulouse, France aut The journal of nutrition, health & aging Springer-Verlag 17/3(2013-03-01), 259-262 1279-7707 17:3<259 2013 17 12603 https://doi.org/10.1007/s12603-012-0434-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12603-012-0434-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Arango-Lopera V. Education Department at Instituto de Geriatría, México D.F, México aut NATIONALLICENCE 700 1- Arroyo P. Research Department at Instituto de Geriatría, México D.F, México aut NATIONALLICENCE 700 1- Gutiérrez-Robledo Luis Instituto de Geriatría, México D.F, México aut NATIONALLICENCE 700 1- Perez-Zepeda M. Research Department at Instituto de Geriatría, México D.F, México aut NATIONALLICENCE 700 1- Cesari M. Gerontopole; Toulouse, France aut NATIONALLICENCE 773 0- The journal of nutrition, health & aging Springer-Verlag 17/3(2013-03-01), 259-262 1279-7707 17:3<259 2013 17 12603 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer