naa a22 4500 51078626X CHVBK 20180411083303.0 cr unu---uuuuu 180411e20130301xx s 000 0 eng 10.1007/s12603-012-0400-x doi (NATIONALLICENCE)springer-10.1007/s12603-012-0400-x Postprandial interleukin-6 response in elderly with abdominal obesity and metabolic syndrome [Elektronische Daten] [P. Moreira, M. Dalboni, M. Cendoroglo, G. Santos, Maysa Cendoroglo] Objective: The aim of this study is to evaluate the contribution of central obesity to inflammatory responses in the postprandial state in elderly patients with and without metabolic syndrome (MetS). Material/Methods: We evaluated 80 elderly individuals who were distributed into three groups: MetS, abdominal obesity (AbObes) and Control, according to ATPIII criteria. Interleukin-6 (IL-6) serum concentration was measured at 0, 2, 4 and 6 hours after the ingestion of a physiological meal without an overload of fat. Results: Serum IL-6 increased 6 hours after the meal in all of the groups (P<0.001). Comparing the groups, there was no difference in the area under the curve (AUC) of IL-6 in the postprandial state. There was a correlation between the 6-hour changes in the concentrations of IL-6 and the homeostasis model assessment of insulin resistance (HOMA-IR) (r = 0.25, P<0.05). Conclusion: In this study, differences in abdominal circumference (AC) have not determined a different behavior of IL-6 in the postprandial state, despite the correlation between AC and IL-6. However, we found that, in the elderly, there is a rise in serum IL-6 at 6 hours. Serdi and Springer-Verlag France, 2012 Aging nationallicence inflammation nationallicence fat-diet nationallicence fatty-acid nationallicence HOMA-IR nationallicence Moreira P. Nutrition Program, Federal University of São Paulo, São Paulo, Brazil aut Dalboni M. Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil aut Cendoroglo M. Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil aut Santos G. Division of Applied Statistics, Federal University of São Paulo, São Paulo, Brazil aut Cendoroglo Maysa Division of Geriatric and Gerontology, Federal University of São Paulo, São Paulo, Brazil aut The journal of nutrition, health & aging Springer-Verlag 17/3(2013-03-01), 206-210 1279-7707 17:3<206 2013 17 12603 https://doi.org/10.1007/s12603-012-0400-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12603-012-0400-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Moreira P. Nutrition Program, Federal University of São Paulo, São Paulo, Brazil aut NATIONALLICENCE 700 1- Dalboni M. Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil aut NATIONALLICENCE 700 1- Cendoroglo M. Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil aut NATIONALLICENCE 700 1- Santos G. Division of Applied Statistics, Federal University of São Paulo, São Paulo, Brazil aut NATIONALLICENCE 700 1- Cendoroglo Maysa Division of Geriatric and Gerontology, Federal University of São Paulo, São Paulo, Brazil aut NATIONALLICENCE 773 0- The journal of nutrition, health & aging Springer-Verlag 17/3(2013-03-01), 206-210 1279-7707 17:3<206 2013 17 12603 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer