naa a22 4500 510786294 CHVBK 20180411083303.0 cr unu---uuuuu 180411e20131201xx s 000 0 eng 10.1007/s12603-013-0370-7 doi (NATIONALLICENCE)springer-10.1007/s12603-013-0370-7 Impact of functional status on the onset of nosocomial infections in an acute care for elders unit [Elektronische Daten] [Sylvie Mazière, P. Couturier, G. Gavazzi] Objective: To assess the role of functional status as a risk factor for nosocomial infections in the elderly. Design: Prospective study. Setting: Acute care for elders units of university hospital of Grenoble. Participant: All patients over 75 years old consecutively hospitalized between January and April 2007. Measurement: The main judgement criteria was the rate of nosocomial infection during the hospital stay, defined according to the French technical comity against nosocomial infections. Other data included functional status at baseline and admission (Katz' ADL), usual risk factors for nosocomial infections, demographic and geriatric assessment data. Results: The study included 223 patients. The mean age was 86.7±6.5 years. A nosocomial infection was diagnosed for 17.0% of the patients. In univariate analysis, the number of medicines, pressure sore, pneumonia diagnosis, illness severity, indwelling bladder catheter, IADL at baseline, and all disability parameters (ADL at baseline, ADL at admission, recent functional decline) were significantly associated with nosocomial infection (p<0.05). In multivariate analysis considering functional status at admission, indwelling bladder catheter (OR=4.43), severe disability at admission (OR=4.42) and illness severity (OR=2.68) were independently associated with nosocomial infection (p<0.05). In a second analysis considering functional status at baseline, only disability at baseline was independently associated with the onset of a nosocomial infection (OR=2.21). Conclusion: Our results suggest a significant impact of functional impairment on the incidence of nosocomial infections in hospitalized elderly population. Disability is a higher risk factor for nosocomial infections than the usual and well-known other parameters. Larger prospective studies are needed to examine the power of this relationship. Serdi and Springer-Verlag France, 2013 Nosocomial infections nationallicence elderly nationallicence functional impairment nationallicence Mazière Sylvie Clinique de médecine gériatrique CHU A. Michallon, 38043, Grenoble cedex 09, France aut Couturier P. Clinique de médecine gériatrique CHU A. Michallon, 38043, Grenoble cedex 09, France aut Gavazzi G. Clinique de médecine gériatrique CHU A. Michallon, 38043, Grenoble cedex 09, France aut The journal of nutrition, health & aging Springer Paris 17/10(2013-12-01), 903-907 1279-7707 17:10<903 2013 17 12603 https://doi.org/10.1007/s12603-013-0370-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12603-013-0370-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mazière Sylvie Clinique de médecine gériatrique CHU A. Michallon, 38043, Grenoble cedex 09, France aut NATIONALLICENCE 700 1- Couturier P. Clinique de médecine gériatrique CHU A. Michallon, 38043, Grenoble cedex 09, France aut NATIONALLICENCE 700 1- Gavazzi G. Clinique de médecine gériatrique CHU A. Michallon, 38043, Grenoble cedex 09, France aut NATIONALLICENCE 773 0- The journal of nutrition, health & aging Springer Paris 17/10(2013-12-01), 903-907 1279-7707 17:10<903 2013 17 12603 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer