naa a22 4500 510786634 CHVBK 20180411083304.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s12603-013-0024-9 doi (NATIONALLICENCE)springer-10.1007/s12603-013-0024-9 Direct effects of leisure-time physical activity on walking speed [Elektronische Daten] [Thaddeus Haight, M. Van Der Laan, I. Tager] Objective: This study quantifies the effects of leisure-time physical activity (LTPA) on walking speed independently of body composition in an elderly cohort, and in those elderly with metabolic derangements due to age, diabetes, and cardiovascular disease (CVD). Methods: 1655 community-dwelling women and men >55 years were measured for body composition (lean mass: fat mass ratio, LNFAT), based on estimated bioelectric impedance by using population-specific prediction equations derived from dual-energy x-ray absorptiometry. In addition to LNFAT, LTPA, diabetes, CVD, walking speed, and other covariates were measured biannually over an 8-year period. LTPA was categorized as <22.5 Mets/week, ≥ 22.5 Mets/week, based on public-health recommended guidelines, and LNFAT was dichotomized based on its sex-specific median. Direct effects of high vs. low LTPA on walking speed were estimated for fixed levels of LNFAT, which represented an intermediary variable in the analysis. Stratified estimates of effects were obtained using subject status (e.g., age≥75 years, diabetes, CVD) at each visit. Results: Walking speed was significantly greater (0.74, 0.75 m/s in women and men, respectively) if subjects experienced LTPA ≥22.5 Mets/week and > median LNFAT, compared with <22.5 Mets/week and ≤ median LNFAT (0.68, 0.69 m/s). While direct effects of LTPA contributed to higher walking speed, none were significant in the overall, nor the stratified groups of subjects, of either sex. Conclusions: Walking speed increases with greater LTPA and LNFAT in the elderly, but there was no evidence to indicate that walking speed increases from LTPA independently of body composition and the metabolic processes it represents. Serdi and Springer-Verlag France, 2013 Leisure-time physical activity nationallicence body composition nationallicence walking speed nationallicence Haight Thaddeus Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA aut Van Der Laan M. Division of Biostatistics, School of Public Health, University of California, Berkeley, USA aut Tager I. Division of Epidemiology School of Public Health, University of California, Berkeley, CA, USA aut The journal of nutrition, health & aging Springer Paris 17/8(2013-10-01), 666-673 1279-7707 17:8<666 2013 17 12603 https://doi.org/10.1007/s12603-013-0024-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12603-013-0024-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Haight Thaddeus Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA aut NATIONALLICENCE 700 1- Van Der Laan M. Division of Biostatistics, School of Public Health, University of California, Berkeley, USA aut NATIONALLICENCE 700 1- Tager I. Division of Epidemiology School of Public Health, University of California, Berkeley, CA, USA aut NATIONALLICENCE 773 0- The journal of nutrition, health & aging Springer Paris 17/8(2013-10-01), 666-673 1279-7707 17:8<666 2013 17 12603 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer