naa a22 4500 510786723 CHVBK 20180411083304.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s12603-013-0039-2 doi (NATIONALLICENCE)springer-10.1007/s12603-013-0039-2 Promoting access to innovation for frail old persons [Elektronische Daten] IAGG (International Association of Gerontology and Geriatrics), WHO (World Health Organization) and SFGG (Societe Francaise de Geriatrie et de Gerontologie) workshop — Athens January 20-21, 2012 [G. Berrut, S. Andrieu, I. Araujo De Carvalho, J. Baeyens, H. Bergman, B. Cassim, F. Cerreta, M. Cesari, H. Cha, L. Chen, A. Cherubini, M. Chou, A. Cruz-Jentoft, L. De Decker, P. Du, B. Forette, F. Forette, A. Franco, R. Guimaraes, L. Gutierrez-Robledo, J. Jauregui, V. Khavinson, W. Lee, L. Peng, C. Perret-Guillaume, M. Petrovic, F. Retornaz, K. Rockwood, L. Rodriguez-Manas, C. Sieber, G. Spatharakis, O. Theou, E. Topinkova, B. Vellas, Athanase Benetos] Abstract: Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate. Objectives: The purpose of this paper is to present expert's positions on the main aspects of the frailty syndrome in the older persons. Participants: Workshop organized by International Association of Gerontology and Geriatrics (IAGG), World Health Organization (WHO) and Société Française de Gériatrie et de Gérontologie (SFGG). Results: Frailty is widely recognized as an important risk factor for adverse health outcomes in older persons. This can be of particular value in evaluating non-disabled older persons with chronic diseases but today no operational definition has been established. Nutritional status, mobility, activity, strength, endurance, cognition, and mood have been proposed as markers of frailty. Another approach calculates a multidimensional score ranging from "very fit” to "severely frail,” but it is difficult to apply into the medical practice. Frailty appears to be secondary to multiple conditions using multiple pathways leading to a vulnerability to a stressor. Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.), as well as social factors (isolation, financial situation) are involved in the vulnerability process. In clinical practice, detection of frailty is of major interest in oncology because of the high prevalence of cancer in older persons and the bad tolerance of the drug therapies. Presence of frailty should also be taken into account in the definition of the cardiovascular risks in the older population. The experts of the workshop have listed the points reached an agreement and those must to be a priority for improving understanding and use of frailty syndrome in practice. Conclusion: Frailty in older adults is a syndrome corresponding to a vulnerability to a stressor. Diagnostic tools have been developed but none can integrate at the same time the large spectrum of factors and the simplicity asked by the clinical practice. An agreement with an international common definition is necessary to develop screening and to reduce the morbidity in older persons. Serdi and Springer-Verlag France, 2013 Older persons nationallicence frailty nationallicence vulnerability nationallicence diagnostic and workshop nationallicence Berrut G. Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes, Nantes, France aut Andrieu S. Gérontopole, Service de Santé Publique, CHU de Toulouse, Toulouse, France aut Araujo De Carvalho I. Department of Gender, Women and Health, World Health Organization (WHO), Geneva, Switzerland aut Baeyens J. Department of Geriatric Medicine, Damiaan General Hospital, Ostend, Belgium aut Bergman H. Department of Family Medicine, Mc Gill University, Montreal, Canada aut Cassim B. Department of Geriatrics, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa aut Cerreta F. European Medicines Agency (EMA), London, UK aut Cesari M. Gérontopole, Service de Santé Publique, CHU de Toulouse, Toulouse, France aut Cha H. Department of Social Welfare, Hallym University, Chuncheon, Gangwon-do, South Korea aut Chen L. Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan aut Cherubini A. Geriatrics, IRCCS-INRCA, Ancona, Italy aut Chou M. Geriatric Medicine Center, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan aut Cruz-Jentoft A. Geriatric Department, Hospital Universitario Ramón y Cajal, Madrid, Spain aut De Decker L. Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes, Nantes, France aut Du P. Academic Research Office, Remnin University, Beijing, China aut Forette B. Hôpital Sainte Perrine, Paris, France aut Forette F. ILC-International Longevity Center, Paris, France aut Franco A. Département de Médecine Gériatrique, CHU de Nice, Nice, France aut Guimaraes R. School of Health Sciences, Brasília, Brazil aut Gutierrez-Robledo L. Instituto Nacional de Geriatría, Mexico City, Mexico aut Jauregui J. Hospital Italiano, Buenos Aires, Argentina aut Khavinson V. St Petersburg Institute of Bioregulation and Gerontology, St Petersburg, Russia aut Lee W. Division of Geriatric Medicine, Taipei Veterans General Hospital, Yuanshan Branch, I-Lan, Taiwan aut Peng L. Division of Geriatric Medicine, Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan aut Perret-Guillaume C. Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy, France aut Petrovic M. Department of Geriatrics, Ghent University Hospital, Ghent, Belgium aut Retornaz F. Centre Gérontologique Départemental, Marseille, France aut Rockwood K. Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada aut Rodriguez-Manas L. Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain aut Sieber C. Friedrich-Alexander-University, Erlangen-Nuernberg, Germany aut Spatharakis G. Public Primary Health Center of Itea, Phokida, Greece aut Theou O. Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada aut Topinkova E. Department of Geriatrics, First Faculty of Medicine, Charles University, Prague, Czech Republic aut Vellas B. INSERM 1027, Toulouse, France aut Benetos Athanase Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy, France aut The journal of nutrition, health & aging Springer Paris 17/8(2013-10-01), 688-693 1279-7707 17:8<688 2013 17 12603 https://doi.org/10.1007/s12603-013-0039-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12603-013-0039-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Berrut G. Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes, Nantes, France aut NATIONALLICENCE 700 1- Andrieu S. Gérontopole, Service de Santé Publique, CHU de Toulouse, Toulouse, France aut NATIONALLICENCE 700 1- Araujo De Carvalho I. Department of Gender, Women and Health, World Health Organization (WHO), Geneva, Switzerland aut NATIONALLICENCE 700 1- Baeyens J. Department of Geriatric Medicine, Damiaan General Hospital, Ostend, Belgium aut NATIONALLICENCE 700 1- Bergman H. Department of Family Medicine, Mc Gill University, Montreal, Canada aut NATIONALLICENCE 700 1- Cassim B. Department of Geriatrics, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa aut NATIONALLICENCE 700 1- Cerreta F. European Medicines Agency (EMA), London, UK aut NATIONALLICENCE 700 1- Cesari M. Gérontopole, Service de Santé Publique, CHU de Toulouse, Toulouse, France aut NATIONALLICENCE 700 1- Cha H. Department of Social Welfare, Hallym University, Chuncheon, Gangwon-do, South Korea aut NATIONALLICENCE 700 1- Chen L. Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan aut NATIONALLICENCE 700 1- Cherubini A. Geriatrics, IRCCS-INRCA, Ancona, Italy aut NATIONALLICENCE 700 1- Chou M. Geriatric Medicine Center, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan aut NATIONALLICENCE 700 1- Cruz-Jentoft A. Geriatric Department, Hospital Universitario Ramón y Cajal, Madrid, Spain aut NATIONALLICENCE 700 1- De Decker L. Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes, Nantes, France aut NATIONALLICENCE 700 1- Du P. Academic Research Office, Remnin University, Beijing, China aut NATIONALLICENCE 700 1- Forette B. Hôpital Sainte Perrine, Paris, France aut NATIONALLICENCE 700 1- Forette F. ILC-International Longevity Center, Paris, France aut NATIONALLICENCE 700 1- Franco A. Département de Médecine Gériatrique, CHU de Nice, Nice, France aut NATIONALLICENCE 700 1- Guimaraes R. School of Health Sciences, Brasília, Brazil aut NATIONALLICENCE 700 1- Gutierrez-Robledo L. Instituto Nacional de Geriatría, Mexico City, Mexico aut NATIONALLICENCE 700 1- Jauregui J. Hospital Italiano, Buenos Aires, Argentina aut NATIONALLICENCE 700 1- Khavinson V. St Petersburg Institute of Bioregulation and Gerontology, St Petersburg, Russia aut NATIONALLICENCE 700 1- Lee W. Division of Geriatric Medicine, Taipei Veterans General Hospital, Yuanshan Branch, I-Lan, Taiwan aut NATIONALLICENCE 700 1- Peng L. Division of Geriatric Medicine, Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan aut NATIONALLICENCE 700 1- Perret-Guillaume C. Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy, France aut NATIONALLICENCE 700 1- Petrovic M. Department of Geriatrics, Ghent University Hospital, Ghent, Belgium aut NATIONALLICENCE 700 1- Retornaz F. Centre Gérontologique Départemental, Marseille, France aut NATIONALLICENCE 700 1- Rockwood K. Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Rodriguez-Manas L. Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain aut NATIONALLICENCE 700 1- Sieber C. Friedrich-Alexander-University, Erlangen-Nuernberg, Germany aut NATIONALLICENCE 700 1- Spatharakis G. Public Primary Health Center of Itea, Phokida, Greece aut NATIONALLICENCE 700 1- Theou O. Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Topinkova E. Department of Geriatrics, First Faculty of Medicine, Charles University, Prague, Czech Republic aut NATIONALLICENCE 700 1- Vellas B. INSERM 1027, Toulouse, France aut NATIONALLICENCE 700 1- Benetos Athanase Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy, France aut NATIONALLICENCE 773 0- The journal of nutrition, health & aging Springer Paris 17/8(2013-10-01), 688-693 1279-7707 17:8<688 2013 17 12603 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer