naa a22 4500 51078688X CHVBK 20180411083305.0 cr unu---uuuuu 180411e20130201xx s 000 0 eng 10.1007/s12603-012-0375-7 doi (NATIONALLICENCE)springer-10.1007/s12603-012-0375-7 Merckel cell carcinoma: The impact of multidisciplinary management [Elektronische Daten] [S. Miranda, X. Gbaguidi, P. Carvalho, P. Chassagne] Merkel cell carcinoma (MMC) is a rare primary neuroendocrine skin tumor associated with a poor prognosis. MMC is histologically similar to small cell lung carcinoma. The incidence of MCC is increasing with a median age of discovery of approximately 70 years old. Treatment of MCC, which usually occurs in sun-exposed skin, includes surgery with reconstruction associated with radiotherapy and/or chemotherapy for advanced stages including widespread metastases. We report two cases of Merkel cell carcinoma in 76 and 84 year old patients and describe the natural history of this cancer and management in geriatric patients. Merkel cell carcinoma (MCC) is a rare cancer with high malignant potential that mainly affects people over the age of 65. It must be diagnosed early to improve the prognosis. The survival rate at 5 years for local or regional invasion is 65%. The median survival for metastasized stages is 10 months. The therapeutic regimen recommended for the treatment of MCC is influenced by the geriatric status of patients, and a multidisciplinary oncogeriatric approach could be of interest. Serdi and Springer-Verlag France, 2013 Merkel Cell Carcinoma nationallicence comprehensive geriatric assessement nationallicence oncogeriatric nationallicence aged nationallicence Miranda S. Geriatrics department, Rouen University hospital, Rouen, France aut Gbaguidi X. Geriatrics department, Dieppe's hospital center, Dieppe, France aut Carvalho P. Dermatology clinic, Rouen University hospital, Rouen, France aut Chassagne P. Geriatrics department, Rouen University hospital, Rouen, France aut The journal of nutrition, health & aging Springer-Verlag 17/2(2013-02-01), 196-198 1279-7707 17:2<196 2013 17 12603 https://doi.org/10.1007/s12603-012-0375-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12603-012-0375-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Miranda S. Geriatrics department, Rouen University hospital, Rouen, France aut NATIONALLICENCE 700 1- Gbaguidi X. Geriatrics department, Dieppe's hospital center, Dieppe, France aut NATIONALLICENCE 700 1- Carvalho P. Dermatology clinic, Rouen University hospital, Rouen, France aut NATIONALLICENCE 700 1- Chassagne P. Geriatrics department, Rouen University hospital, Rouen, France aut NATIONALLICENCE 773 0- The journal of nutrition, health & aging Springer-Verlag 17/2(2013-02-01), 196-198 1279-7707 17:2<196 2013 17 12603 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer