naa a22 4500 510799256 CHVBK 20180411083347.0 cr unu---uuuuu 180411e20130801xx s 000 0 eng 10.1007/s12028-013-9856-8 doi (NATIONALLICENCE)springer-10.1007/s12028-013-9856-8 Hypothermia After CPR Prolongs Conduction Times of Somatosensory Evoked Potentials [Elektronische Daten] [Aline Bouwes, Patty Doesborg, D. Laman, Johannes Koelman, Jaap Imanse, Selma Tromp, Björn van Geel, Elly van der Kooi, Eveline Zandbergen, Janneke Horn] Background: To investigate the effect of mild hypothermia on conduction times and amplitudes of median nerve somatosensory evoked potentials (SEP) in patients after cardiopulmonary resuscitation (CPR). Methods: Patients treated with hypothermia after CPR who underwent SEP recording during hypothermia and after rewarming were selected from a prospectively collected database. Latencies and amplitudes of N9 (peripheral conduction time, PCT), N13, and N20 were measured. The central conduction time (CCT) was defined as peak-peak latency N13-N20. Recordings of 25 patients were assessed by a second observer to determine the intraclass correlation coefficient (ICC). Results: A total of 115 patients were included. The mean body temperature at SEP during hypothermia was 33.1°C (SD 0.8) and after rewarming 37.1°C (SD 0.8). Mean latencies of N9, N13, and N20 and mean CCT were longer during hypothermia. There were no consistent differences in amplitudes. There was an almost perfect ICC for assessment of latencies and amplitudes. Conclusions: This study showed that PCT and CCT of median nerve SEP were prolonged during treatment with hypothermia after CPR compared with after rewarming. Amplitudes did not differ consistently. Springer Science+Business Media New York, 2013 Prognosis [17] nationallicence Coma [18] nationallicence Evoked potentials/somatosensory [288] nationallicence Cardiac [290] nationallicence Critical care [295] nationallicence Bouwes Aline Department of Intensive Care, Room C3-423, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut Doesborg Patty Department of Intensive Care, Room C3-423, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut Laman D. Department of Neurology and Clinical Neurophysiology, Sint Lucas Andreas Hospital, P.O. Box 9243, 1006 AE, Amsterdam, The Netherlands aut Koelman Johannes Departments of Neurology and Clinical Neurophysiology, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut Imanse Jaap Department of Neurology, Onze Lieve Vrouwe Gasthuis, P.O. Box 95500, 1090 HM, Amsterdam, The Netherlands aut Tromp Selma Department of Clinical Neurophysiology, St. Antonius Hospital, P.O. Box 2500, 3430 EM, Nieuwegein, The Netherlands aut van Geel Björn Department of Neurology, Medical Center Alkmaar, P.O. Box 501, 1800 AM, Alkmaar, The Netherlands aut van der Kooi Elly Department of Neurology, Medical Center Leeuwarden, P.O. Box 888, 8901 BR, Leeuwarden, The Netherlands aut Zandbergen Eveline Department of Neurology, Rijnstate Hospital, P.O. Box 9555, 6800 TA, Arnhem, The Netherlands aut Horn Janneke Department of Intensive Care, Room C3-423, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut Neurocritical Care Springer US; http://www.springer-ny.com 19/1(2013-08-01), 25-30 1541-6933 19:1<25 2013 19 12028 https://doi.org/10.1007/s12028-013-9856-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12028-013-9856-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bouwes Aline Department of Intensive Care, Room C3-423, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Doesborg Patty Department of Intensive Care, Room C3-423, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Laman D. Department of Neurology and Clinical Neurophysiology, Sint Lucas Andreas Hospital, P.O. Box 9243, 1006 AE, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Koelman Johannes Departments of Neurology and Clinical Neurophysiology, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Imanse Jaap Department of Neurology, Onze Lieve Vrouwe Gasthuis, P.O. Box 95500, 1090 HM, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Tromp Selma Department of Clinical Neurophysiology, St. Antonius Hospital, P.O. Box 2500, 3430 EM, Nieuwegein, The Netherlands aut NATIONALLICENCE 700 1- van Geel Björn Department of Neurology, Medical Center Alkmaar, P.O. Box 501, 1800 AM, Alkmaar, The Netherlands aut NATIONALLICENCE 700 1- van der Kooi Elly Department of Neurology, Medical Center Leeuwarden, P.O. Box 888, 8901 BR, Leeuwarden, The Netherlands aut NATIONALLICENCE 700 1- Zandbergen Eveline Department of Neurology, Rijnstate Hospital, P.O. Box 9555, 6800 TA, Arnhem, The Netherlands aut NATIONALLICENCE 700 1- Horn Janneke Department of Intensive Care, Room C3-423, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Neurocritical Care Springer US; http://www.springer-ny.com 19/1(2013-08-01), 25-30 1541-6933 19:1<25 2013 19 12028 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer