naa a22 4500 510799701 CHVBK 20180411083349.0 cr unu---uuuuu 180411e20131001xx s 000 0 eng 10.1007/s12028-013-9843-0 doi (NATIONALLICENCE)springer-10.1007/s12028-013-9843-0 Contrast-Induced Nephropathy in Patients with Aneurysmal Subarachnoid Hemorrhage [Elektronische Daten] [Vamsidhar Chavakula, Bradley Gross, Kai Frerichs, Rose Du] Introduction: Patients with aneurysmal subarachnoid hemorrhage (SAH) frequently undergo multiple angiographic studies within a 48-h period. We sought to evaluate the impact of these repeated contrast loads on renal function. Methods: We reviewed the records of a consecutive series of 104 patients with aneurysmal subarachnoid hemorrhage, most of whom underwent at least an initial CT angiogram and digital subtraction angiography. Six patients had baseline renal disease. Initial creatinine levels were compared to maximum levels over a subsequent 48-h period after their last angiographic study. We defined contrast-induced nephropathy (CIN) as an increase in creatinine of at least 0.3 from baseline. Results: The mean change in creatinine following treatment was 0.05±0.23, with three patients developing CIN (2.9%). In 2 cases of CIN, the creatinine increase was inconsequential (0.39 and 0.44). All patients with CIN had an early return of their creatinine to baseline; none required dialysis or suffered permanent sequelae as a result of these creatinine increases. There was no statistically significant difference in the rate of CIN in patients treated with microsurgical clipping (n=85) as compared to those who underwent coiling (n=19). Conclusion: Our results underscore the relative safety of the usage of multiple angiographic studies performed in patients with aneurysmal SAH, particularly in patients without baseline renal disease. Springer Science+Business Media New York, 2013 Aneurysm nationallicence Subarachnoid hemorrhage nationallicence Contrast nationallicence Angiography nationallicence Nephropathy nationallicence Coiling nationallicence Clipping nationallicence Chavakula Vamsidhar Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut Gross Bradley Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut Frerichs Kai Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut Du Rose Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut Neurocritical Care Springer US; http://www.springer-ny.com 19/2(2013-10-01), 157-160 1541-6933 19:2<157 2013 19 12028 https://doi.org/10.1007/s12028-013-9843-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12028-013-9843-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chavakula Vamsidhar Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Gross Bradley Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Frerichs Kai Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Du Rose Department of Neurological Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA aut NATIONALLICENCE 773 0- Neurocritical Care Springer US; http://www.springer-ny.com 19/2(2013-10-01), 157-160 1541-6933 19:2<157 2013 19 12028 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer